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Am J Perinatol 2005; 22(6): 287-297
DOI: 10.1055/s-2005-870659
REVIEW ARTICLE

Copyright © 2005 by Thieme Medical Publishers, Inc., 333 Seventh Avenue, New York, NY 10001, USA.

Preterm Premature Rupture of Membranes: Perspectives Surrounding Controversies in Management

Kjersti M. Aagaard-Tillery1 , Francis S. Nuthalapaty2 , Patrick S. Ramsey2 , Kirk D. Ramin3
  • 1Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, University of Utah Health Sciences, Salt Lake City, Utah
  • 2Division of Maternal-Fetal Medicine, Center for Research in Women’s Health, University of Alabama at Birmingham, Birmingham, Alabama
  • 3Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, University of Minnesota, Minneapolis, Minnesota
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Publication History

Publication Date:
13 July 2005 (online)

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ABSTRACT

Preterm premature rupture of the membranes (PPROM) occurs in approximately 3% of all pregnancies, and accounts for one third of all preterm births. Despite its prevalence, optimal management of PPROM remains largely undefined and lacks conformity. In this article, we review the pathophysiology of PPROM, and summarize the available literature describing various management strategies in an effort to define current controversies in the management of PPROM.

KEYWORDS

Preterm premature rupture of membranes - prematurity - pregnancy

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Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, University of Minnesota

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