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Synfacts 2005(1): 0156-0156  
DOI: 10.1055/s-2005-872139
Metal-Mediated Synthesis
© Georg Thieme Verlag Stuttgart · New York

Multicomponent Reactions Based on Dilithio Ketone α,β-Dianions

Contributor(s): Paul Knochel, Andrei Gavryushin
S. Yamato, G. Yamamura, M. Komatsu, M. Arai, T. Fukuyama, I. Ryu*
Osaka University and Osaka Prefecture University, Japan
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Publication History

Publication Date:
21 September 2005 (online)

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Significance

Ketones are widespread functional entities in a number of synthetic targets. The method allows creating polyfunctionalized structures with a ketone framework, introducing three different electrophiles in a ‘one-pot’ procedure.