Total Synthesis of Stephacidin A

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Synfacts 2005(1): 0103-0103
DOI: 10.1055/s-2005-872155

Synthesis of Natural Products and Potential Drugs

Contributor(s): Philip Kocienski
P. S. Baran*, C. A. Guerrero, N. B. Ambhaikar, B. D. Hafensteiner
Scripps Research Institute, La Jolla, USA

Further Information

Publication Date:
21 September 2005 (online)

Stephacidins A and B are metabolites of Aspergillus ochraceus. Both are potent antitumour agents that appear to have a novel mechanism of action.