ABSTRACT
From a neuro-ophthalmologic standpoint, five areas may be affected by psychogenic disease: (1) vision, including visual acuity and visual field; (2) ocular motility and alignment; (3) pupillary size and reactivity; (4) eyelid position and function; and (5) corneal and facial sensation. The physician faced with a patient complaining of decreased vision or some other disturbance related to the afferent or efferent visual systems for which there is no apparent biologic explanation has three responsibilities. First, the physician must ascertain that an organic disorder is not present. Second, the physician should induce the patient to see or do something that would not be possible if the condition were organic in nature. Finally, the physician should attempt to determine whether the patient has an underlying psychiatric disease or is experiencing psychosocial stress. In this article, manifestations of psychogenic disease as they pertain to vision are considered, and, where appropriate, the various methods used to diagnose and treat these phenomena are discussed.
KEYWORDS
Visual loss - visual field constriction - nonorganic - dilated pupil - spasm of near reflex - ptosis - blepharospasm
REFERENCES
1
Yamade S, Kono M, Hukami K.
Color vision in psychogenic visual disturbance.
Folia Ophthalmol Jpn.
1989;
40
1674-1680
2
Weller M, Wiedemann P.
Hysterical symptoms in ophthalmology.
Doc Ophthalmol.
1989;
73
1-33
3
Newman N J.
Neuro-ophthalmology and psychiatry.
Gen Hosp Psychiatry.
1993;
15
102-114
4
Scott J A, Egan R A.
Prevalence of organic neuro-ophthalmologic disease in patients with functional visual loss.
Am J Ophthalmol.
2003;
135
670-675
5
Clarke W N, Noël L P, Bariciak M.
Functional visual loss in children: a common problem with an easy solution.
Can J Ophthalmol.
1996;
31
311-313
6
Taich A, Crowe S, Kosmorsky G S, Traboulsi E I.
Prevalence of psychosocial disturbances in children with nonorganic visual loss.
J AAPOS.
2004;
8
457-461
7
Kathol R G, Cox T A, Corbett J J et al..
Functional visual loss: follow-up of 42 cases.
Arch Ophthalmol.
1983;
101
729-735
8
Keltner J L, May W N, Johnson C A et al..
The California syndrome: functional visual complaints with potential economic impact.
Ophthalmology.
1985;
92
427-435
9
Mouriaux F, Defoort-Dhellemmes S, Kochman F et al..
Le pithiatisme oculaire chez l'enfant et l'adolescent.
J Fr Ophtalmol.
1997;
20
175-182
10
Langmann A, Lindner S, Kriechbaum N.
Funktionelle Sehstauorung als Konversionssymptom im Kindes-und jugendalter.
Klin Monatsbl Augenheilkd.
2001;
218
677-681
11
Trauzettel-Klosinski S.
Untersuchungsstrategien bei Simulation und funkionellen Sehstauorungen.
Klin Monatsbl Augenheilkd.
1997;
211
73-83
12
Bienfang D C, Kurtz D.
Management of functional visual loss.
J Am Optom Assoc.
1998;
69
12-21
13
Rieken H.
Die Spiegelraumbewegung, eine neue Untersuchungsmethode auf der Grundlage eines “psycho-optischen” reflexes.
Albrecht Von Graefes Arch Ophthalmol.
1943;
145
432-453
14
Kramer K K, La Piana F G, Appleton B.
Ocular malingering and hysteria: diagnosis and management.
Surv Ophthalmol.
1979;
24
89-96
15
Thompson H S.
Functional visual loss.
Am J Ophthalmol.
1985;
100
209-213
16
Tsutsui J, Karino T, Kimura H et al..
Evaluation of vision tests in the diagnosis of malingering.
Folia Ophthalmol Jpn.
1985;
36
1159-1164
17 Miller N R. Neuro-ophthalmologic manifestations of nonorganic disease . In: Miller NR, Newman NJ, Biousse V, Kerrison JB Walsh and Hoyt's Clinical Neuro-Ophthalmology. 6th ed. Vol. 1. Baltimore; Williams & Wilkins 2005: 1315-1334
18
Levy N S, Glick E B.
Stereoscopic perception and Snellen visual acuity.
Am J Ophthalmol.
1974;
78
722-724
19
Donzis P B, Rappazzo J A, Burde R M et al..
Effect of binocular variations of Snellen's visual acuity on Titmus stereoacuity.
Arch Ophthalmol.
1983;
101
930-932
20
Nakamura A, Akio T, Matsuda E et al..
Pattern visual evoked potentials in malingering.
J Neuroophthalmol.
2001;
21
42-45
21
Xu S, Meyer D, Yoser S et al..
Pattern visual evoked potential in the diagnosis of functional visual loss.
Ophthalmology.
2001;
108
76-81
22
Thompson J C, Kosmorsky G S, Ellis B D.
Fields of dreamers and dreamed-up fields: functional and fake perimetry.
Ophthalmology.
1996;
103
117-125
23
Ohkubo H.
Visual field in hysteria-reliability of visual field by Goldmann perimetry.
Doc Ophthalmol.
1989;
71
61-67
24
Lincoff H A.
Bilateral central scotomas of hysterical origin.
Arch Ophthalmol.
1959;
62
273-279
25
Gittinger Jr J W.
Functional hemianopsia: a historical perspective.
Surv Ophthalmol.
1988;
32
427-432
26
Fish R H, Kline L B, Hanumanthu V K et al..
Hysterical bitemporal hemianopia “cured” with contact lenses.
J Clin Neuroophthalmol.
1990;
10
76-78
27 Pilley S FJ, Thompson H S. Binasal field loss and prefixation blindness . In: Glaser JS, Smith JL Neuro-Ophthalmology Symposium of the University of Miami and the Bascom Palmer Eye Institute. Vol. 8. St Louis; CV Mosby 1975: 277-284
28
Garvey J L.
Hysteric homonymous hemianopia.
Am J Ophthalmol.
1922;
5
721-722
29
Massicotte E C, Semela L, Hedges III T R.
Multifocal visual evoked potential in nonorganic visual field loss.
Arch Ophthalmol.
2005;
123
364-367
30
Catalono R A, Simon J W, Krohel G B et al..
Functional visual loss in children.
Ophthalmology.
1986;
93
385-390
31 Stark L, Hoyt W F, Ciuffreda K J et al.. Voluntary nystagmus consists of overlapping and truncated saccades: an oculographic and control systems analysis . In: Zuber BL Models of Oculomotor Behavior and Control. Boca Raton, FL; CRC Press 1981: 75-89
32
Zahn J R.
Incidence and characterization of voluntary nystagmus.
J Neurol Neurosurg Psychiatry.
1978;
41
617-623
33
Shults W T, Stark L, Hoyt W F et al..
Normal saccadic structure of voluntary nystagmus.
Arch Ophthalmol.
1977;
95
1399-1404
34 Stark L, Shults W T, Ciuffreda K J et al.. Voluntary nystagmus is saccadic: evidence from motor and sensory mechanisms. In: Proceedings of the Joint Automatic Control Conference, San Francisco . Pittsburgh; Instrument Society of America 1977: 1410-1414
35
Krohel G, Griffin J F.
Voluntary vertical nystagmus.
Neurology.
1979;
29
1153-1154
36
Blair C J, Goldberg M F, von Noorden G K.
Voluntary nystagmus.
Arch Ophthalmol.
1967;
77
349-354
37
Ciuffreda K J.
Voluntary nystagmus: new findings and clinical implications.
Am J Optom Physiol Opt.
1980;
57
795-800
38
Keane J R.
Neuro-ophthalmologic signs and symptoms of hysteria.
Neurology.
1982;
32
757-762
39
Sarkies N JC, Sanders M D.
Convergence spasm.
Trans Ophthalmol Soc UK.
1985;
104
782-786
40
Rosenberg M L.
Spasm of the near reflex mimicking myasthenia gravis.
J Clin Neuroophthalmol.
1986;
6
106-108
41
Manor R S.
Use of special glasses in treatment of spasm of near reflex.
Ann Ophthalmol.
1979;
11
903-905
42 Loewenfeld I E. The Pupil: Anatomy, Physiology, and Clinical Applications. Vol. I. Ames, IA; Iowa State University Press 1993
43 Bumke O. Die Pupillenstörungen in Geisteskranken. Vienna; Fischer Verlag 1904
44
Westphal A.
Über Bisher nicht beschriebene Pupillenerscheinungen in Katatonischen Stupor mit Krankendemonstrationen.
Allg Z Psychiatr.
1907;
64
694-701
45
Westphal A.
Über ein im Katatonischen Stupor beiobachtestes Pupillenphaenomen sowie bemerkungen über die pupillenstarre bei hysterie.
Dtsch Med Wochenschr.
1907;
33
1080-1085
46
Tyrer J H, Sutherland J M, Eadie M J.
Myosis bilatéral dans les déviations volontaires des yeux dans toutes les directions, dans un syndrome de neuromyélite optique.
Rev Neurol.
1963;
109
72-76
47
Thompson H S, Newsom D A, Loewenfeld I E.
The fixed dilated pupil: sudden iridoplegia or mydriatic drops? A simple diagnostic test.
Arch Ophthalmol.
1971;
86
21-27
48
Cavenar J, Brantley I J, Braasch E.
Blepharospasm: organic or functional?.
Psychosomatics.
1978;
19
623-628
49 Walsh F B, Hoyt W F. Clinical Neuro-Ophthalmology. 3rd ed. Vol. 3. Baltimore; Williams & Wilkins 1969: 2530
Neil R MillerM.D.
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