Abstract
A range of aromatic organocopper or organomagnesium compounds undergo smooth cross-coupling reactions with aryl bromides, chlorides, fluorides and tosylates, leading to polyfunctionalized aromatics or heterocycles in the presence of cobalt salts (5-7.5 mol%) as catalysts. Very mild reaction conditions are needed and, in the case of cross-coupling with organocopper compounds, Bu4 NI (1 equiv) and 4-fluorostyrene (20 mol%) are essential as promoters for successful couplings.
Key words
cross-coupling - transition metals - magnesium - heterocycles - halides
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