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Synfacts 2007(2): 0225-0225  
DOI: 10.1055/s-2006-955783
Polymer-Supported Synthesis
© Georg Thieme Verlag Stuttgart · New York

P-B Bond Cleavage with Polymer-Supported Amines

Contributor(s): Yasuhiro Uozumi, Yoichi M. A. Yamada
S. Sayalero, M. A. Pericàs*
Institute of Chemical Research of Catalonia, Tarragona and Universitat de Barcelona, Spain
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Publication History

Publication Date:
23 January 2007 (online)

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Significance

A facile new method for the deprotection of organophosphorus-borane complexes using polymer-supported piperazines was developed. Thus, the reactions of organophosphorus-borane complexes were performed with a pipera­zinomethyl polystyrene resin (2-5 mol equiv) in toluene or THF for 1.5-22 h at 60-115 °C to give the corresponding deprotected phosphorus compounds in 68-100% yield (10 substrates). The products were isolated by a simple filtration without further purification.