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Synfacts 2007(2): 0189-0189
DOI: 10.1055/s-2006-955855
DOI: 10.1055/s-2006-955855
Metal-Catalyzed Asymmetric Synthesis and Stereoselective Reactions
© Georg Thieme Verlag Stuttgart · New York
Pd-HETPHOX Catalyzed Asymmetric Intramolecular Heck Reaction
M. O. Fitzpatrick, A. G. Coyne, P. J. Guiry*
University College Dublin, Ireland
Further Information
Publication History
Publication Date:
23 January 2007 (online)

Significance
The authors recently reported on the use of the ligands developed by Tietze and coworkers, HETPHOX (L. F. Tietze, J. K. Lohmann Synlett 2002, 2083-2085), in asymmetric intermolecular Heck reactions (Synlett 2004, 106-110). In the present paper, they focus on the synthesis of enantioenriched spirooxindoles using an intramolecular Heck cyclization.