ABSTRACT
Propofol is the nearly ideal agent for office-based plastic surgery. Among all anesthetic
agents, only propofol has the ability to elicit happiness in this special group of
patients. Cosmetic surgery patients will tolerate discomfort in preference to postoperative
nausea and vomiting. Propofol is a powerful antiemetic agent. Patient safety will
not be optimized unless the person responsible for the administration of propofol
has airway management skills. Dedicated anesthesia providers are highly skilled in
airway management. Although the short half-life of propofol is seductive for a fast-acting,
rapid emerging anesthetic, interindividual differences in propofol response make measurement
of the target organ (i.e., the brain) with a bispectral index (BIS) monitor very important.
BIS levels < 45 for > 1 hour are associated with increased 1-year anesthesia mortality
thought to be associated with an inflammatory response. The only currently available
way to avoid overmedicating with propofol is to monitor with a level of consciousness
monitor like BIS.
KEYWORDS
Propofol - anesthesia - BIS monitor - office-based plastic surgery - ketamine
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Barry L FriedbergM.D.
Clinical Assistant Professor in Anesthesia, Volunteer Faculty, Department of Anesthesia,
University of Southern California
3535 E. Coast Hwy, PMB 103, Corona del Mar, CA 92625-2104