Literatur
-
1 World Health Organization .Health Report 2005.
-
2
Weinstein A R, Sesso H D, Lee I M et al.
Relationship of physical activity vs body mass index with type 2 diabetes in women.
JAMA.
2004;
292
1188-1194
-
3
Hebebrand J, Friedel S, Schäuble N et al.
Perspectives: molecular genetic research in human obesity.
Obes Rev.
2003;
4
139-146
-
4
Frayling T M, Timpson N J, Weedon M N et al.
A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity.
Science.
2007;
11 (316)
889-894
-
5
Klöting N, Schleinitz D, Ruschke K et al.
Inverse relationship between obesity and FTO gene expression in visceral adipose tissue in humans.
Diabetologia.
2008;
51
641-647
-
6
Ohlson L O, Larsson B, Svardsudd K et al.
The influence of body fat distribution on the incidence of diabetes mellitus. 13.5 years of follow-up of the participants in the study of men born in 1913.
Diabetes.
1985;
34
1055-1058
-
7
Klöting N, Stumvoll M, Blüher M.
The biology of visceral fat.
Internist (Berl).
2007;
48
126-133
-
8
Harman-Boehm I, Blüher M, Redel H et al.
Macrophage infiltration into omental versus subcutaneous fat across different populations: effect of regional adiposity and the comorbidities of obesity.
J Clin Endocrinol Metab.
2007;
92
2240-2247
-
9
Bashan N, Dorfman K, Tarnovscki T et al.
Mitogen-activated protein kinases, inhibitory-kappa B kinase, and insulin signaling in human omental versus subcutaneous adipose tissue in obesity.
Endocrinology.
2007;
148
2955-2962
-
10
Youn B S, Klöting N, Kratzsch J et al.
Serum vaspin concentrations in human obesity and type 2 diabetes.
Diabetes.
2008;
57
372-377
-
11
Klöting N, Graham T E, Berndt J et al.
Serum retinol-binding protein is more highly expressed in visceral than in subcutaneous adipose tissue and is a marker of intra-abdominal fat mass.
Cell Metab.
2007;
6
79-87
-
12
Blüher M, Engeli S, Klöting N et al.
Dysregulation of the peripheral and adipose tissue endocannabinoid system in human abdominal obesity.
Diabetes.
2006;
55
3053-3060
-
13
Blüher M, Stumvoll M.
Role of muscle and fat tissue in the pathogenesis of type 2 diabetes.
Dtsch Med Wochenschr.
2006;
131
S 231-S 235
-
14
Abel E D, Peroni O, Kim J K et al.
Adipose-selective targeting of the GLUT4 gene impaires insulin action in muscle and liver.
Nature.
2001;
409
729-733
-
15
Blüher M, Michael M D, Peroni O D et al.
Adipose tissue selective insulin receptor knockout protects against obesity and obesity-related glucose intolerance.
Dev Cell.
2002;
3
25-38
-
16
Blüher M, Kahn B B, Kahn C R.
Extended longevity in mice lacking the insulin receptor in adipose tissue.
Science.
2003;
299
572-574
-
17
Berndt J, Kovacs P, Ruschke K et al.
Fatty acid synthase gene expression in human adipose tissue: association with obesity and type 2 diabetes.
Diabetologia.
2007;
50
1472-1480
-
18
Ferrannini E, Natali A, Bell P et al.
Insulin resistance and hypersecretion in obesity.
J Clin Invest.
1997;
100
1166-1173
-
19
Knudtson M D, Klein B E, Klein R et al.
Associations with weight loss and subsequent mortality risk.
Ann Epidemiol.
2005;
15
483-491
1 Anlässlich der Verleihung des Ferdinand-Bertram-Preises der DDG 2008
Prof. Dr. med. M. Blüher
Medizinische Klinik und Poliklinik III, Universität Leipzig
Philipp-Rosenthal-Straße 27
04103 Leipzig
Phone: 03 41 / 9 71 33 80
Fax: 03 41 7 9 71 33 89
Email: bluma@medizin.uni-leipzig.de