RSS-Feed abonnieren
Bitte kopieren Sie die angezeigte URL und fügen sie dann in Ihren RSS-Reader ein.
https://www.thieme-connect.de/rss/thieme/de/10.1055-s-00000131.xml
Synfacts 2008(10): 1009-1009
DOI: 10.1055/s-2008-1078284
DOI: 10.1055/s-2008-1078284
Synthesis of Natural Products and Potential Drugs
© Georg Thieme Verlag
Stuttgart ˙ New York
Synthesis of Callipeltoside C
Rezensent(en):Phiip KocienskiJ. Carpenter, A. B. Northrup, D. Chung, J. J. M. Weiner, S.-G. Kim, D. W. C. MacMillan*
Princeton University and Caltech, Pasadena, USA
Total Synthesis and Structural Revision of Callipeltoside C
Angew. Chem. Int. Ed. 2008, 47: 3568-3572
Princeton University and Caltech, Pasadena, USA
Total Synthesis and Structural Revision of Callipeltoside C
Angew. Chem. Int. Ed. 2008, 47: 3568-3572
Weitere Informationen
Publikationsverlauf
Publikationsdatum:
22. September 2008 (online)
Key words
callipeltoside C - organocatalysis - aldols - α-oxyamination - palladium
Significance
Proline catalysis of two directed aldol reactions and an α-oxyamination reaction are salient features of a very concise and efficient synthesis of callipeltoside C.
Comment
This first synthesis of callipeltoside C established the correct absolute stereochemistry of the pendent 2-O-methylevalose (N).