ABSTRACT
Epilepsy surgery treatment should be considered as standard of care for all patients with medically intractable partial-onset epilepsy who are found to be good surgical candidates based on their presurgical evaluation. Delaying surgical treatment continues to be a problem among neurologists. The early recognition of pharmacoresistance and patients' referral for presurgical evaluation can shorten the time to identify potential surgical candidates. A successful early surgery can be expected to significantly improve these patients' quality of life, not only because of a seizure-free state but also by improving psychiatric comorbidities. Vagal nerve stimulation (VNS) is currently the only FDA-approved neurostimulation treatment strategy for patients who are not considered candidates for epilepsy surgery. VNS has been shown to decrease seizure frequency by approximately 50% in 30 to 40% of implanted patients. The future of epilepsy surgery and neurostimulation for those individuals with medically intractable partial-onset epilepsy shows great promise.
KEYWORDS
Intractable epilepsy - temporal lobe epilepsy - frontal lobe epilepsy - mesial temporal sclerosis - neurostimulation
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Antoaneta BalabanovM.D.
Department of Neurological Sciences, Rush University Medical Center
1653 West Congress Parkway, Chicago, IL 60612
Email: Antoanetta_J_Balabanov@rush.edu
