Leg venous ulcer healing process after application of membranous dressing with silver ions

M. Kucharzewski; K. Wilemska-Kucharzewska; M. Kózka; M. Spałkowska

doi:10.12687/phleb2141-6-2013

Phlebologie, Inhaltsverzeichnis

Phlebologie 2013; 42(06): 340-346
DOI: 10.12687/phleb2141-6-2013

Original article

Schattauer GmbH

Leg venous ulcer healing process after application of membranous dressing with silver ions

Heilungsgeschwindigkeit des venösen Beinulkus nach Applikation einer Silberionen-haltigen Wundauflage

Authors

M. Kucharzewski

¹Department of Descriptive and Topographic Anatomy, Medical University of Silesia, Zabrze, Poland

²Outpatient Surgery Center no. 2, Specialist Hospital no. 2, Bytom, Poland
K. Wilemska-Kucharzewska

²Outpatient Surgery Center no. 2, Specialist Hospital no. 2, Bytom, Poland
M. Kózka

³5^th Military Hospital, Cracow, Poland
M. Spałkowska

³5^th Military Hospital, Cracow, Poland

Abstract

Summary

Aim: To assess the efficiency of application of new membranous dressing with silver ions in patients with chronic venous ulceration.

Methods: 58 patients were divided randomly into two groups. In group A (n=30) mean ulcer surface area was 8.52 cm², in group B (n=28) mean wound surface area was 8.29 cm². In group A membranous dressings with silver ions (Textus Bioactiv^® by Biocell GmbH, Germany) were used. In group B hydrocolloid dressing Unna’s boot was applied. All dressings were changed every 7 days until the wound was completely healed. Changes in wound area were calculated and the speed of healing process was measured every week with healing per day index (cm²/day).

Results: After 7 weeks ulcers healed in all patients of group A. Ulcers in group B healed after 16 weeks of treatment.

Conclusion: On the basis of this outcome the authors concluded that application of membranous dressing with silver ions speeds up the process of treating chronic lower leg ulceration.

Zusammenfassung

Ziel der Studie: Die Effektivität der Applikation einer neuen Wundauflage mit Silberionen wurde an Patienten mit chronischer Beinulze-ration getestet.

Methode: 58 Patienten wurden zufällig in zwei Gruppen geteilt. Bei Gruppe A (n=30) betrug die durchschnittliche Ulkusfläche 8,52 cm², in Gruppe B (n=28) durchschnittlich 8,29 cm². Die Patienten der Gruppe A wurden mit einer Silberionen-haltigen Wundauflage versorgt (Textus Bioactiv^® Biocell GmbH, Deutschland). Gruppe B wurde mit einer Hydrokolloid-Auflage (Unna’s boot) versorgt. Alle Auflagen wurden 1-mal pro Woche gewechselt bis die Wunde verheilt war. Die Veränderungen der Wundfläche wurden wöchentlich berechnet, ebenso die Geschwindigkeit des Heilungsprozesses (cm²/Tag).

Ergebnisse: Ulzera in Gruppe A waren nach 7 Wochen Behandlung geheilt, in Gruppe B nach 16 Wochen.

Schlussfolgerung: Auf der Basis dieser Ergebnisse schlussfolgern die Autoren, dass die Auflagen mit Silberionen den Heilungsprozess chronischer Beinulzera beschleunigen.

Keywords

Venous leg ulcer - membranous dressing - silver ions

Schlüsselwörter

Venöser Beinulkus - Wundauflage - Silberionen

Volltext

Referenzen

Reference
1 Dissemond J. Differenzialdiagnosen des Ulcus cruris venosum. Phlebologie 2011; 40: 85-92.
2 Kucharzewski M, Œlezak A, Franek A. Topical treatment of non – healing venous leg ulcers by cellulose membrane. Phlebologie 2003; 32: 147-151.
3 Rippon M, Davies P, White R, Bosanquet N. The economic impact of hard-to-heal leg ulcers. Wounds 2007; 3: 59-69.
4 Baker S, Stacey M, Jopp-McKay A, Hoskin S, Thompson P. Epidemiology of chronic venous ulcers. Br J Surg 1991; 78: 864-867.
5 Carpentier P, Maricq H, Biro C. et al. Prevalence, risk factors, and clinical patterns of chronic venous disorders of lower limbs: a population based study in France. J Vasc Surg 2004; 40: 650-659.
6 Nelson EA. Venous leg ulcer. BMJ Clinical Evidence 2011; 12: 1902-2011.
7 Reeder SWI, de Roos K-P, Vogels RJM, Neumann HAM. E-survey on venous leg ulcer among Dutch dermatologists. Phlebologie 2013; 42 (05) 270
8 Kahle B. Foam sclerotherapy of ulcus cruris venosum. Phlebologie 2010; 39 (03) 121-188.
9 Stoffels-Weindorf M, von der Stück H, Klode Dissemond J. Treatment pathways for patients with chronic wounds in Germany. Results of a prospective study in 100 patients with chronic leg ulcers. Phlebologie 2013; 42: 177-240.
10 Zabel M. Ulcus cruris in differential dermatological diagnosis. Phlebologie 2010; 39: 163-166.
11 Trent JT, Falabella A, Eaglstein WH, Kirsner R. Venous ulcers: pathophysiology and treatment options. Ostomy Wound Manage. 2005 May;. 51 (05) 38-54. quiz 55-6
12 Schwahn-Schreiber C. Surgery of ulcus cruris venosum. Phlebologie 2010; 39: 156-162.
13 Eberhardt RT, Raffetto JD. Chronic Venous Insufficiency. Circulation 2005; 111: 2398-2409.
14 Coleridge S. et al. Causes of venous ulceration: a new hypothesis. Br Med J 1998; 296: 1726-1727.
15 Nees S, Juchem G, Weiss DR, Partsch H. Pathogenesis and therapy of chronic venous disease: New insights into structure and function of the leg venous system. Phlebologie 2012; 41: 246-257.
16 Cullum N, Nelson EA, Fleming K. et al. Systematic reviews of wound care management. Health Tech Assess 2001; 5: 1-227.
17 Taradaj J, Franek A, Brzezinska-Wcislo L, Blaszczak E, Polak A. Randomized trial of medical compression stockings versus twolayer short-stretch bandaging in the management of venous leg ulcers. Phlebologie 2009; 38: 157-163.
18 Butler CM, Coleridge S. Microcirculatory aspects of venous ulceration. J Dermatol Surg Oncol 1994; 20: 474-480.
19 Scott HJ, Coleridge S, Scurr JH. Histological study of white blood cells and their association with lipodermatosclerosis and venous ulceration. Br J Surg 1991; 78: 210-211.
20 Goldman MP, Franek A. The Aleksander House Group Consensus paper on venous leg ulcer. J Dermatol Surg Oncol 1992; 25: 965-987.
21 Martin M. Dynamisches Wundheilungsprofil des venösen Ulcus cruris. VASA 1994; 6: 1-5.
22 Margolis DJ, Gross EA, Wood CR, Lazerus GS. Planimetric rate of healing in venous ulcers of the leg treated with pressure bandage and hydrocolloid dressing. J Am Acad Dermatol 1993; 28: 418-421.
23 Gilman TH. Parameter for measurement of wound closure. Wounds 1990; 3: 95-101.