Synfacts
Issue 08 · August 2012
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SYNFORM
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Synthesis of Natural Products and Potential Drugs
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0811
Synthesis of a CB1 Cannabinoid Receptor Antagonist
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0812
Synthesis of (
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Synthesis of (–)-Berkelic Acid
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Synthesis of Anominine and Tubingensin A
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Synthesis of a Telithromycin Analogue
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0816
Synthesis of (–)-13-Oxyingenol and Its Natural Derivative
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0817
Synthesis of a Glucosylceramide Synthase Inhibitor
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0818
Synthesis of (+)-Gelsemine
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0819
Synthesis of an Akt Kinase Inhibitor
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0820
Synthesis of Pellasoren A
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0821
Synthesis of (+)-Chimonanthine
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0822
Synthesis of (
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0823
Synthesis of PF-00951966
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0824
Synthesis of a Glucokinase Activator
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0825
Synthesis of LY500307
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0826
Synthesis of Doxercalciferol
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0827
Synthesis of (–)-Mersicarpine
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0828
Synthesis of AZD6906
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Synthesis of Heterocycles
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0829
Au-Catalyzed Carbonyl Migration for the Synthesis of Azepinoindol-1-ones
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0830
One-Pot Pd-Catalyzed Synthesis of Isoquinolines and Furo/Thienopyridines
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PDF (101 kb)
0831
Synthesis of Isoquinolin-1(2
H
)-ones via Pd-Catalyzed Isocyanide Coupling
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0832
Synthesis of Piperazine-2,5-diones via a Convenient Dieckmann Cyclization
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0833
A Cu-Catalyzed Double C–N Coupling Approach to Cinnolines
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0834
Functionalized Enantioenriched Dihydropyrans by [4+2] Cycloaddition
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0835
DABCO-Mediated [4+2] Annulation Approach to 2,3-Dihydropyran-4-ones
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0836
Selectivity in Palladium-Catalyzed Carboesterification – Amides versus Esters
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0837
Synthesis of Benzofuro[3,2-
d
]pyrimidines from 3-Chlorochromones
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0838
Synthesis and Suzuki Coupling of 2-Aryl-Trisubstituted Oxazoles
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0839
Indoloazocines via a Sequential Ugi–Gold-Catalyzed Hydroarylation
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0840
Polysubstituted Pyridines via Re-Catalyzed Alkyne Insertion
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0841
Synthesis of 3-Carboxylated Indoles from 2-Ethynylanilines and CO
2
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0842
Iron-Catalyzed Substitution of Benzoxazoles and Benzothiazoles
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0843
Palladium-Catalyzed Synthesis of Indoles via Oxidative C–H Activation
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Synthesis of Materials and Unnatural Products
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0845
Polyethylene from Trimethylsulfoxonium Halide in Water
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0846
Stabilized Heptacene for n-Type Materials
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0847
Large Twisted Acenes
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0848
Stable Boron–Boron Triple Bond
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0849
Highly Flexible COT
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0850
π-Conjugated Polycycle Containing Boron
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0851
Zipping Oligo-Alkynes into Aromatic Ribbons
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0852
Sensing Chirality of α-Hydroxyl Carboxylic Acids with a Fluorescent Polymer
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0853
Activated Alumina Activates C–F Bonds: A New Route to PAHs
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0854
Synthesis of New Types of Subporphyrins
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0855
π-Expanded Diketopyrrolopyrrole Dyes
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0856
Diastereoselective [2+2+2] Cycloisomerization in the Synthesis of Helicenes
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Metal-Catalyzed Asymmetric Synthesis and Stereoselective Reactions
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0857
Palladium-Catalyzed Asymmetric Quaternary Stereocenter Formation
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0858
Sc-Catalyzed Enantioselective Allylation of Isatins
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0859
Rh-Catalyzed Addition of Arylboronic Acids to α,β-Unsaturated Sulfonyls
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0860
Asymmetric, Titanium-Mediated Aldol-Type Enamide–Aldehyde Cyclization
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0861
Copper-Catalyzed Highly Diastereoselective [3+3] Cycloaddition
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0862
Rh-Catalyzed Amination of Tertiary Allylic Trichloroacetimidates
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0863
Zinc–ProPhenol-Catalyzed Asymmetric Spirannulation of α-Hydroxyoxindoles
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0864
Chiral Tin Dibromide Catalyzed Enantioselective
N
-Nitroso Aldol Reaction
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0865
Asymmetric Allylic Alkylation of Pyrroles and 4,7-Dihydroindoles
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0866
Asymmetric Epoxidations of Enones Mediated by Non-Heme Iron Catalysts
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0867
Enantioselective Synthesis of Pyridylcarbinols
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0868
Copper-Catalyzed Synthesis of Heterobicyclo[3.1.1]heptan-6-ones
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0869
Iridium-Catalyzed Asymmetric Synthesis of
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-3-Fluoro-1-alcohols
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0870
Rhodium-Catalyzed Cyclopropanation of Azido Alkenes
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0871
Ru-Catalyzed Asymmetric Hydrogenation of Unsaturated β-Keto Esters
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0872
Inversion of Chirality by Redox-Induced Catalyst Reconfiguration
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0873
Palladium-Catalyzed Asymmetric Allylic Alkylation of Pyrroles
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0874
Palladium-Catalyzed Asymmetric 6-
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0875
Au-Catalyzed Enantioselective Cope Rearrangement
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0876
Ion-Paired Ligands for Palladium-Catalyzed Asymmetric Allylation
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0877
Catalytic Hydrogenation for the Preparation of Alkyl Boron Compounds
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0878
Multinuclear Cu-Catalyzed Asymmetric Conjugate Addition
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0879
Pd-Catalyzed Asymmetric Synthesis of Indolines
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0880
Palladium-Catalyzed Asymmetric Synthesis of Dibenzosiloles
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0881
Ru-Catalyzed Enantioselective Addition of Amines to Styrenes
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0882
Ni-Catalyzed Ring Opening of Cyclopropanes with Amines
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0883
Scandium-Catalyzed Enantioselective Epoxidation of Chalcones
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0884
Au(I)-Catalyzed Asymmetric Hydroamination of Racemic Allenes
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0885
Cu-Catalyzed Reductive Coupling of Alkenylazaarenes with Ketones
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Metal-Mediated Synthesis
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0887
Cu-Catalyzed/Ru-Photocatalyzed Trifluoromethylation of Boronic Acids
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0888
Co-Catalyzed Asymmetric Addition of Acetylenes to Benzonorbornadienes
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0889
Alkylmagnesium Reagents from Boron–Magnesium Exchange
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0890
One-Pot Synthesis of 4-Aryl-
N
-methyl-1,2,3,4-tetrahydroisoquinolines
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0891
β-Arylation of Ketones by a 1,4-Addition Sequence under Flow Conditions
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0892
Asymmetric Ring Opening of Aziridines with Halides
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0893
Amide-Forming Ligation of Acyltrifluoroborates and Hydroxylamines
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0894
Novel Lewis Acid ATNP for Vinylogous Aldol Reactions
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0895
Asymmetric Synthesis of Secondary Nitriles via Negishi Cross-Coupling
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0896
Intramolecular Vinylation of Organolithiums
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0897
Synthesis of Fluorinated Cyclopropanes
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0898
Mes
2
Mg-Mediated Shapiro Reactions of Tosylhydrazones
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0899
New Iron Thiolate Complexes for Cross-Coupling Reactions
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0900
Synthesis of 1,4-Dihydropyridines and Pyridines out of
N
-Allyl Ynamides
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0901
Ni-Catalyzed Alkylation of Purines and Benzimidazoles with Grignard Reagents
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Organo- and Biocatalysis
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0903
Organocatalytic Approach to N−H Insertion Reactions
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0904
Vinylogous Michael Addition Catalyzed by Cinchona Thiourea
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0905
Catalytic Asymmetric 1,6-Addition of Alkyl Thiol to Cyclic Dienones
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0906
Regiodivergent Asymmetric Allylic Alkylation
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0907
Asymmetric Fluorination of Enamides
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0908
α-Vinylation of Aldehydes via Combination of Copper and Aminocatalysis
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0909
[4+2] Cycloaddition Catalyzed by Quinine-Derived Primary Amine
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0910
Modified Cinchona Amine Catalyzed Epoxidation of 2-Cyclopentenones
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0911
Catalytic Asymmetric Ring-Opening Reactions of Aziridines
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0912
Enzymatic Reductive Amination of Diketones
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Polymer-Supported Synthesis
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0913
Asymmetric Michael Addition of Aldehydes to Nitroalkenes Using JH-CPP
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0914
Aerobic Oxidation of α-Hydroxy Ketones with CaO
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0915
Epoxidation of Olefins with a Silica-Supported Peracid in Flowing
sc
CO
2
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0916
Au/MoO
x
-Catalyzed Aerobic Oxidation of Alcohols
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0917
A RuNPs-Based Supramolecular Hydrogel for Hydrogenation of Alkenes
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0918
DMAP-Embedded Nanoporous Conjugated Polymer
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0919
Asymmetric Hydrogenation of Ketones with Cp*RhTsDPEN-POSS
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0920
Direct Synthesis of Vitamin K
4
Using Bifunctional Heterogeneous Catalyst
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0921
One-Pot Sonogashira–Click Coupling with a Cu-Pd MOF Catalyst
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0922
Suzuki Coupling with Polymer-Supported Pd Nanoparticles in Water
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0923
A
3
-Coupling Using TiO
2
-Supported Copper Nanoparticles
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0924
Asymmetric Aldol Reaction with a Polymeric Organocatalyst
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0925
Ring Opening of Epoxides Catalyzed by Graphene Oxide
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0926
Hydration of Nitriles to Amides with Fe
3
O
4
@SiO
2
–Ru Catalyst
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Addenda and Errata
0927
Synthesis of Acrivastine
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0927
Ullmann Diaryl Etherification with Copper Fluorapatite
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Erratum
0927
Synthesis of (+)-Scholarisine A
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