DOI: 10.1055/s-00000131

Synfacts

Issue 12 · Volume 8 · December 2012 DOI: 10.1055/s-002-24043

Synform

A122
Zanda, Matteo: SYNFORM ISSUE 2012/12

Synthesis of Natural Products and Potential Drugs

z1279
All PDFs of this category
1279
Synthesis of the CGRP Receptor Antagonist BMS-846372
1280
Formal Total Syntheses of Didehydrostemofoline and Isodidehydrostemofoline
1281
Synthesis of (−)-205B
1282
Synthesis of Piragliatin
1283
Synthesis of Bixafen
1284
Total Synthesis of (+)-Ibophyllidine
1285
Total Synthesis of (±)-Gracilamine
1286
Formal Synthesis of Ezetimibe
1287
Total Syntheses of Incarviditone and Incarvilleatone
1288
Synthesis of AM-1638
1289
Synthesis of DS-8108b
1290
Synthesis of (–)-Huperzine A
1291
Enantioselective Synthesis of (+)-Cubitene
1292
Enantioselective Total Synthesis of Prostaglandin PGF2α in Seven Steps
1293
Synthesis of LY411575

Synthesis of Heterocycles

z1295
All PDFs of this category
1295
Palladium-Catalyzed Cyclization of Electron-Deficient Enynes
1296
A Palladium-Catalyzed Multicomponent Heteroannulation Route to Indoles
1297
A Pd-Catalyzed C–H Activation Route to Benzisoxazolones
1298
Rhodium-Catalyzed Synthesis of 3-Aryl Indoles from 1-Sulfonyl 1,2,3-Triazoles
1299
Synthesis of Sultams via Rh(III)-Catalyzed Directed C–H Activation
1300
Synthesis of Imidazopyridines by Cu(II)/Fe(III) Co-catalyzed C–N Coupling
1301
Synthesis of 5-Acyl-2-amino-1,3,4-thiadiazoles From Acid Chlorides
1302
Synthesis of Functionalized Azaindolines and Azatetrahydroquinolines
1303
Stereoselective Access to Quaternary Carbon Atoms via SN2 Cleavage of Azetidinium Ions
1304
Ru-Catalyzed Synthesis of Polysubstituted Pyrazoles
1305
Copper–Silver Cocatalyzed Synthesis of Pyrazoloisoquinolines
1306
Synthesis of 3-Aminoindolizines Enabled by Flow Technology
1307
Synthesis of Cyclic Azomethine Imines as Precursors to β-Aminocarbonyl Scaffolds
1308
Copper-Catalyzed Synthesis of 1,4-Dihydroazete Derivatives
1309
Cu- and Ni-Catalyzed Regioselective Synthesis of Disubstituted Pyrroles

Synthesis of Materials and Unnatural Products

z1311
All PDFs of this category
1311
Breaking the B≡N Bond for 1,4-Azaborines
1312
A Two-Step Procedure to Brominated 2-Alkoxythiophenes
1313
Radical Dearomatization and Two-Electron Reduction of a Redox-Active Ligand
1314
A Stable Phosphinonitrene
1315
Triphenylene-Based Electron-Deficient Discotic Liquid Crystals
1316
A Tetrabenzoporphyrin Precursor in Four Steps
1317
From Carboxylic Acids to Alkyl Bromides by Reductive Bromination
1318
Extending Porphyrinoids with Fused Anthracenes
1319
A FRET Donor–Acceptor Copolymer with Spatially Alternating Transition Dipoles
1320
Regioselective Synthesis of Fused Anthracenes
1321
Synthesis of Photocleavable Star Polymers by the ‘Brush-First’ Method
1322
Mild Gold-Catalyzed Biaryl Synthesis

Metal-Catalyzed Asymmetric Synthesis and Stereoselective Reactions

z1323
All PDFs of this category
1323
Counteranion-Directed Tsuji–Trost Reaction
1324
Solvent- or Temperature-Controlled Diastereoselective Aldol Reaction
1325
Nickel-Catalyzed Intermolecular [2+2] Cycloaddition
1326
Palladium-Catalyzed Cycloisomerization of 1,n-Dienes via a Chain-Walking Mechanism
1327
Ru–NHC Catalyzed Asymmetric Hydrogenation of Benzothiophenes
1328
Ru(CO)-salen Catalyzed Aziridination of Vinyl Ketones
1329
Copper–NHC Catalyzed Conjugate Addition of Grignard Reagents
1330
Iridium-Catalyzed Asymmetric Hydrogenation of N-Benzyl Pyridinium Bromides
1331
Palladium-Mediated Asymmetric Synthesis of 3-Amino-2-oxindoles
1332
Gold Catalyzed Ene–Yne Cyclization for the Formation of Benzo[b]oxepines
1333
Copper–NHC Catalyzed Hydroboration of Propargylic Substrates
1334
Axially Chiral Carbene Gold Complex Catalyzed [4+2] Cycloadditions
1335
Yamamoto, Hisashi; Oda, Susumu: Copper-Catalyzed Asymmetric Henry Reaction
1336
Iridium-Catalyzed Asymmetric Allylation of Trimethylsiloxy Furans
1337
Iridium-Catalyzed Asymmetric Transfer Hydrogenation in Water
1338
Allylation of Cyclopropanols via Zinc–Copper Homoenolates
1339
Palladium-Catalyzed Asymmetric Alkene Carboamination
1340
Palladium-Catalyzed Stereospecific Suzuki–Miyaura Cross-Coupling
1341
Asymmetric Synthesis of β-Aryl-β-Boronyl Enoates
1342
Rh-catalyzed Asymmetric Conjugate Addition to Dihydronitronaphthalenes
1343
Chiral Quaternary Carbons from Organolithiums and Organocuprates
1344
Ruthenium-Catalyzed Formal Arylformylation of E-β-Bromostyrenes with Aldehydes
1345
Ruthenium-Catalyzed C–C Coupling of Dienes to α‑Hydroxy Esters
1346
Silver-Catalyzed Enantioselective Conjugate Addition and Cycloaddition
1347
Merged Au–Enamine Catalysis for Enantioselective α-Allylic Alkylation
1348
Cyclobutenamides by Rhodium-Mediated Formal [2+2] Cycloaddition
1349
Rhodium-Catalyzed Asymmetric Coupling Reactions of Allylic Ethers
1350
Copper-Catalyzed [6+3] Cycloadditions of Azomethine Ylides with Fulvenes
1351
2,6-cis-Tetrahydropyranes via an Asymmetric Tandem Sequence
1352
Kinetic Resolution of N-Acylaziridines

Metal-Mediated Synthesis

z1353
All PDFs of this category
1353
Ruthenium-Catalyzed Hydroboration of Terminal Alkynes
1354
Synthesis of Secondary Aminomethylated Arenes via Cross-Coupling
1355
Stereoselective Cu-Mediated Oxyamination to Yield Morpholines
1356
Difluoromethylation of Lithium Enolates by Umpolung of Fluoroform
1357
Cu-Mediated Trifluoromethylation of Boronic Acids using NaSO2CF3 and TBHP
1358
Cross-Coupling of Benzyl Alcohols with Grignard Reagents
1359
Catalytic Boracarboxylation of Alkynes using B2(pin)2 and CO2
1360
Ruthenium-Catalyzed Transformation of Aryl and Alkenyl Triflates into Halides
1361
Copper-Mediated Trifluoromethylation of α-Diazo Esters with TMSCF3
1362
Iron- and Zink-Mediated Synthesis of Oxazolines and Oxazoles
1363
Boron-to-Zinc Exchange of Allyl Organometallic reagents
1364
Cobalt-Catalyzed Migratory Arylzincation of Alkynes
1365
Ni-Catalyzed Kumada Reaction of Tosylalkanes and Aryltosylethanones
1366
Trifluoromethylation of α-Haloketones with Fluoroform-Derived CuCF3
1367
Electrophilic Trifluoromethanesulfanylation of Organometallic Species

Organo- and Biocatalysis

z1369
All PDFs of this category
1369
Medium Ring Size Bromolactonization
1370
Enantioselective Brønsted Acid Catalyzed Route to Pyrroloindolines
1371
Thiourea-Catalyzed Ring Opening of Episulfonium Ions with Indole Derivatives
1372
Amidine Catalyzed Kinetic Resolution of Lactams and Thiolactams
1373
A Supported Squaramide as a Recyclable Catalyst for Michael Additions
1374
Light-Driven Organocatalytic Synthesis of Benzothiophenes
1375
Organocatalytic Activation of Anthracenes in Asymmetric Diels–Alder Reactions
1376
Cinchona Alkaloid Derivatives Catalyzed Asymmetric [4+2] Cycloaddition

Polymer-Supported Synthesis

z1377
All PDFs of this category
1377
Green LED Responding Photocatalytic Oxidation of Alcohols with Au/CeO2
1378
Preparation of Benzimidazoles via Hydrogen Transfer with Pd/C
1379
Suzuki Coupling With a Supported Pd–Glucosamine Phosphine Complex
1380
Oxidative Esterification and Imination of Alcohols Using Au/MgxAl-HT
1381
Polystyrene-Supported Pd(II) for Heck and Sonogashira Reactions
1382
Au-Nanoparticle-Catalyzed Hydrosilylation of Alkynes
1383
α-Hydroxylation of 1,3-Dicarbonyl Compounds Using PI/CB-Au
1384
A Cooperative Catalytic System for the Aerobic Oxidation of Amines
1385
Asymmetric Henry–Michael Reaction with Bifunctional Catalysts
1386
Controlled Hydrogenation of Nitroarenes Using Ruthenium NPs/Charcoal
1387
Aerobic Oxidation of Alcohols with Pd Nanoparticles on AmP-MCF
1388
Reduction of Nitroarenes and Carbonyl Compounds with Ni–Fe3O4 MNPs
1389
Synthesis of Aryloxypyridines via Pd/C-Catalyzed Suzuki–Miyaura Cross-Coupling