DOI: 10.1055/s-00000131

Synfacts

Issue 02 · Volume 10 · February 2014 DOI: 10.1055/s-004-26302

Synform

A17
Zanda, Matteo: SYNFORM ISSUE 2014/02

Synthesis of Natural Products and Potential Drugs

z111
All PDFs of this category
0111
Synthesis of (S)-Sitagliptin
0112
Total Synthesis of (+)-Methyl N-Decarbomethoxychanofruticosinate
0113
Biogenetically Inspired Synthesis of Indole Alkaloids
0114
Total Synthesis of Montanine-Type Alkaloids
0115
Synthesis of a Glucokinase Activator
0116
Total Synthesis of (±)-Gephyrotoxin
0117
Synthesis of Diaryl Sulfones: GSK 742457
0118
Synthesis of Thuggacin B
0119
Synthesis of Voriconazole
0120
Synthesis of GSK2263167
0121
Synthesis of Renin Inhibitor DS-8108b
0122
Synthesis of (±)-Sculponeatin N
0123
Synthesis of Safingol
0124
Synthesis of (+)-Bermudenynol

Synthesis of Heterocycles

z125
All PDFs of this category
0125
Heteroannulation Route to Benzofurans
0126
Three-Component Synthesis of Rhodanines on Nanoporous Silica
0127
Synthesis of Benzofuranones from Alkynyl Aryl Ethers
0128
Transformation of Sulfonylpyrroles into 6-Azaindoles
0129
Iron(III) Chloride Catalyzed Synthesis of Spirocyclic Pyrimidinones
0130
Ir(III)/Bi(OTf)3-Catalyzed Prins Route to Pyran-Fused Indoles
0131
Synthesis of Substituted Thiophenes from Polyhalogenated Nitrobutadienes
0132
Palladium-Catalyzed Heteroannulation Route to 3-Trifluoromethylbenzofurans
0133
Rhodium-Catalyzed Synthesis of Furo[2,3-b]pyran-6-ones
0134
Synthesis of 2,5-Dihydrofurans via a Petasis Borono-Mannich Reaction
0135
Rhodium-Catalyzed ortho-C–H Acylation Route to 3-Alkylidenephthalides
0136
Synthesis of 1,3-Thiazin-2-ones via an Asymmetric Hetero-Diels–Alder Reaction
0137
Asymmetric Organocatalytic Synthesis of 2,6-Diazabicyclo[2.2.2]octanones
0138
C4-Alkenylation of 3-Formyl Indoles via Ruthenium(II)-Catalyzed C–H Activation
0139
Synthesis of Piperazines via Gold-Catalyzed Cyclization of Propynyl Diamines

Synthesis of Materials and Unnatural Products

z141
All PDFs of this category
0141
Having a Hydrocarbon Ball
0142
Aminyl Tetraradicals Persist at Room Temperature
0143
Four-in-One: Pentafulvalenes via Quadruple Carbopalladation
0144
Gold-Catalyzed Diastereoselective Synthesis of Naphtha[b]cyclobutenes
0145
Zipping Up Thienylbenzenes to Thia[7]helicenes
0146
Two Stable Extended Zethrenes
0147
A Stable, Intra-Sheet π-Conjugated Covalent Organic Framework
0148
A New Record for Proton Sponges
0149
A π-Extended Indenofluorene with Substantial Singlet Biradical Character
0150
Tetracenes in a Bowl-Shaped Arrangement
0151
Programmed Synthesis of Arylthiazoles
0152
High Yielding Synthesis of meso-Substituted Macrocycles
0153
A Simple Reagent for the Difluoroethenylation of Arenes

Metal-Catalyzed Asymmetric Synthesis and Stereoselective Reactions

z155
All PDFs of this category
0155
Asymmetric Allylic Alkylation of Acyclic β‑Keto Esters Catalyzed by Iridium
0156
Asymmetric Addition of Phosphines Catalyzed by P-Chiral Pd Complexes
0157
Enantioselective [3+2] Annulation via C–H Activation Catalyzed by Iridium
0158
Enantioselective Hydrogenation of Nitroolefins by Rhodium Catalysis
0159
[3+3] Cycloaddition of Azomethine Ylides with Azomethine Imines
0160
Synthesis of Axially Chiral Biaryls by a Palladium Catalyst
0161
Asymmetric Ring Opening of Oxabenzonorbornadiene with Amines
0162
Asymmetric Synthesis of QUINAP via Atropselective C–P Coupling
0163
Iron–Schiff Base Catalyzed Asymmetric Hydrophosphonylation
0164
Asymmetric [3+2] Cycloaddition of Disubstituted Nitroalkenes
0165
Kinetic Resolution of Racemic Propargyl Acetates by Palladium Catalysis
0166
Yttrium-Catalyzed Asymmetric Aldol Cyclization of α-Keto Esters
0167
Asymmetric Synthesis of 1,2,4-Triazinane Frameworks by Copper Catalysis
0168
Enantioselective Copper-Catalyzed Oxytrifluoromethylation of Alkenes
0169
Enantioselective Synthesis of γ-Methyl-Substituted Carbonyl Compounds
0170
Asymmetric Sulfoxidation Catalyzed by Mn/Porphyrin
0171
Asymmetric Synthesis of Axially Chiral Biaryls via [2+2+2] Cycloaddition
0172
Co(II)-Based Metalloradical Catalysis for Asymmetric Cyclopropanation
0173
Asymmetric Reduction of 2,2-Dimethyl-4-dioxinones Catalyzed by Ruthenium
0174
Copper-Catalyzed Enantioselective Intramolecular Cannizzaro Reaction
0175
Subsequent Reduction and Jocic-Type Reaction of Trichloromethyl Ketones
0176
Ir-Catalyzed Asymmetric Hydrogenation and Transfer Hydrogenation of Ketones
0177
Rhodium-Catalyzed Enantioselective Hydrogenation of 1-Alkylvinyl Benzoates
0178
Deoxycholic Acid Derived Biaryl Phosphites in Conjugate Addition
0179
[3+3] Cycloaddition of Enol Diazoacetates with N-Acyliminopyridinium Ylides
0180
Asymmetric Conjugate Addition of Arylboronic Acids to Nitroolefins
0181
Dehydrogenative Cross-Coupling of Simple Alkenes and Acrylates
0182
Bisheterocyclizations of Alkynes Catalyzed by Platinum
0183
Iron-Catalyzed Asymmetric Ring Opening of meso-Epoxides

Metal-Mediated Synthesis

z185
All PDFs of this category
0185
N–Bpin-Directed Borylation of (Hetero)Aryls
0186
Fluorination of Aryl Trifluoroboronates with Potassium Fluoride Mediated by Copper
0187
Enantiospecific Transition-Metal-Catalyzed Allylic Alkylation
0188
1,4-Reductive Aldol Reactions of Substituted α,β-Unsaturated Amides
0189
Reductive Coupling and Reduction of Barbituric Acids Using SmI2
0190
Allylation of N-(Quinolin-8-yl)benzamides with Allyl Ethers Catalyzed by Iron
0191
Cyanotrifluoromethylation of Styrenes Using the Togni Reagent and Copper Cyanide
0192
Electrophilic Difluoro(phenylthio)methylation of Allyltrimethylsilanes
0193
gem-Difluoroolefination of Diazo Compounds with TMSCF3 Catayzed by Copper
0194
Cross-Coupling of Silanes with Organic Halides Catalyzed by Copper
0195
Reactions of 2-Pyrone Derivatives with MeMgBr Catalyzed by Iron
0196
Synthesis of 2-Boryl 1,3-Butadienes from α-Alkoxy Allenes Catalyzed by Copper
0197
Substitution of Unactivated Alkyl Fluorides Using YbI3
0198
Base-Dependent Enantiodivergent De-protonation/Acylation of α-Amino Nitriles
0199
One-Pot Synthesis of Polysubstituted Isochromanes

Organo- and Biocatalysis

z201
All PDFs of this category
0201
β-Substituted α-Hydroxy Esters via Dynamic Kinetic Resolution
0202
Boronate Ester Assisted Chiral Carboxylic Acid Catalyzed Aziridination
0203
Direct β-Functionalization of Ketones by Photoredox-Coupled Organocatalysis
0204
A Chiral Tertiary Amine Catalyzed Intermolecular [3+2] Annulation
0205
Conjugate-Base-Stabilized Brønsted Acids in Asymmetric Catalysis
0206
An Organocatalytic Route towards Annulated Indoles
0207
Axially Chiral Amine Catalyzed Asymmetric Hydroxyamination of Aldehydes
0208
Organocatalytic Remote Activation in an Aza-Diels–Alder Reaction
0209
Asymmetric Counteranion-Directed Photoredox Catalysis
0210
Two Fluorinated Compounds from One Organocatalytic Kinetic Resolution
0211
Asymmetric Catalytic α-Benzylation of Aldehydes
0212
Asymmetric Synthesis of Pyrroloindolones by N-Heterocyclic Carbenes

Polymer-Supported Synthesis

z213
All PDFs of this category
0213
Click Reaction with Copper(I)–NHC Supported on Fe3O4/Si
0214
Asymmetric Hydrogenation of Ketones with a PMO-Supported Rhodium Complex
0215
PS-PAr3 Hybrid: Metal Complexation and Catalytic Applications
0216
Direct Amidation from Alcohols and Amines with Polymeric Au or Au/Co
0217
Photocatalyzed Deoxygenation of Styrene Oxides Using TiO2
0218
Strecker and Kabachnik–Fields Reactions with DHAA/Fe3O4
0219
Asymmetric Aldol Reaction Using a Polymeric Hydantoin Auxiliary
0220
Flow Oppenauer Oxidation of Alcohols with Zirconia Oxide
0221
Glassy Carbon-Supported Rhodium(I) Catalysts for Intramolecular Hydroamination
0222
Enantioselective Aldol Reaction in Water with a Supported Prolinamide
0223
Synthesis of Benzoyl Fumarates with Supported Nicotinic Acid Thioester
0224
Aerobic Oxidation with Branched Polystyrene-Supported Gold NPs