DOI: 10.1055/s-00000131

Synfacts

Issue 05 · Volume 10 · May 2014 DOI: 10.1055/s-004-26851

Synform

A59
Zanda, Matteo: SYNFORM ISSUE 2014/05

Synthesis of Natural Products and Potential Drugs

z447
All PDFs of this category
0447
Total Syntheses of Ampelopsin D, Pallidol, and Quadrangularin A
0448
Total Synthesis of Caraphenol A
0449
Synthesis of SMO Inhibitor PF-04449913
0450
Total Synthesis of (±)-Mersicarpine
0451
Total Synthesis of Guttiferone A
0452
Synthesis of an Estrogen-Related Receptor 1 Inhibitor
0453
Synthesis of a TRPV1 Antagonist
0454
Synthesis of Dantrolene
0455
Total Synthesis of (+)-Tubingensin A
0456
Synthesis of (±)-Sorbiterrin A
0457
Synthesis of Podophyllotoxin

Synthesis of Heterocycles

z459
All PDFs of this category
0459
[3+2] Cycloaddition Route to Spirooxindoles
0460
Synthesis of 1,2-Benzisoxazoles by Palladium-Catalyzed [4+1] Annulation
0461
Synthesis of Trisubstituted Oxazoles via a Three-Component, One-Pot Reaction
0462
Efficient C–C Aryl–Heteroaryl Bond Formation by Photoredox Direct Arylation
0463
Pyrroles via Copper-Promoted Oxidative Coupling of Enamides with Alkynes
0464
Construction of Fused Pyrroles from 1,3-Diones and N-Alkynylhydroxyamines
0465
Rhodium-Catalyzed Synthesis of Polysubstituted Indoles from Styryl Azides
0466
Synthesis of Functionalized Pyrroles by a Multi-Component Reaction
0467
One-Pot Asymmetric Synthesis of 2,3-Dihydropyrroles
0468
Ruthenium-Catalyzed Synthesis of Lactams from Cyclic Amines and Water
0469
Rhodium-Catalyzed Synthesis of β-Naphthols and Indenes
0470
Synthesis of Spiromorpholinotetra-hydropyrans Through a Prins Bicyclization
0471
Oxa- versus Thia-Selectivity in the Prins Cyclization
0472
Transition-Metal-Free Synthesis of 1,4-Benzodiazepinones

Synthesis of Materials and Unnatural Products

z473
All PDFs of this category
0473
Extending Arenes via C–H Activation with Rhodium
0474
It Takes 2+2+2 to Tango
0475
Chalcogen α and ω End Groups on P3HT
0476
[5]Cycloparaphenylene: The Smallest Nanohoop
0477
Flying π: ‘Flapping’ Aceneimides with Cyclooctatetraene Cores
0478
Easy as 1, 2, 3: Cyclization to Afford N2-Substituted Benzotriazoles
0479
Fun with [5]Cumulenes and Tetracyanoethylene
0480
Münching up Fullerenes Asymmetrically
0481
Cyclizations with Transient Sulfenic Acids
0482
Alkynes Made-to-Order with Light, in Air and Water
0483
Selective C–H Arylation of Fluorinated Heterocycles

Metal-Catalyzed Asymmetric Synthesis and Stereoselective Reactions

z485
All PDFs of this category
0485
Copper-Catalyzed Diastereoselective Synthesis of Amino Azides
0486
Asymmetric Construction of Alkenyl-Substituted Quaternary Carbons
0487
Asymmetric Friedel–Crafts Reaction Using a Chiral-at-Metal Iridium Catalyst
0488
Stereodivergent Synthesis of Labile Aldehydes via a Dual Catalysis Approach
0489
Asymmetric Iridium-Catalyzed Allyl–Alkene Coupling en route to Chiral 1,5-Dienes
0490
Ruthenium–BINAP Catalytic Hydrogenation on Multikilogram Scale
0491
Chiral Sulfoxide-P Ligands for Palladium-Catalyzed Asymmetric Allylic Alkylation
0492
Asymmetric Zinc-Catalyzed Aldol Reaction of Glycinate Schiff Bases and Aldehydes
0493
Iridium-Catalyzed Intramolecular Asymmetric C–H Functionalization of α-Keto Amides
0494
Diastereoselective Synthesis of N-Sulfonyl α,β-Diamino Acid Derivatives
0495
Rhodium-Catalyzed Addition of Arylboronic Acids to Alkenylazaarenes
0496
Asymmetric Imino Diels–Alder Reaction with an Inverse Electron Demand
0497
Copper-Catalyzed Asymmetric Friedel–Crafts Alkylation of Indoles
0498
Synthesis of β2,2-Amino Acids via Asymmetric Friedel–Crafts Alkylation
0499
Copper-Catalyzed Enantioselective Synthesis of β-Hydroxy-α-amino Acids
0500
Rhodium–Diene Complex Catalyzed Asymmetric Alkenylation
0501
Synthesis of (–)-Aurantioclavine via Intramolecular Allylic Amination
0502
Chiral MOF Catalyst for Asymmetric Cyanation of Aldehydes
0503
Diastereoselective Sequential Aldol Reaction of Disilyl Enolether
0504
Copper-Catalyzed Enantioselective Addition of Nitromethane to 2-Acylpyridine N-Oxides
0505
Copper-Catalyzed Stereoselective Synthesis of (Borylmethyl)cyclopropanes
0506
Asymmetric Hydrogenation of Ketones by Ruthenium Catalysis
0507
Asymmetric Synthesis of 1,3-Dioxolanes via [3+2] Cycloaddition
0508
Rhodium-Catalyzed Insertion of Carbenes into Benzocyclobutenols
0509
Ruthenium-Catalyzed Asymmetric Allylic Amination
0510
Asymmetric Hydrocyanation Using Ru(phgly)2(binap)–MeOLi System
0511
Rhodium Furanoside Monophosphite Catalyzed Asymmetric Hydrogenation
0512
Enantioselective Four-Component Cascade Reaction of Aryldiazoesters
0513
Hydrosilylation of Ketones Catalyzed by Zn–TPS-he-pybox

Metal-Mediated Synthesis

z515
All PDFs of this category
0515
Stereospecific Kumada Cross-Coupling of Alkyl and Aryl Grignards
0516
Zinc-Catalyzed Borylation of Alkyl Halides
0517
O-Arylation of Functionalized Phenols Using Substituted Arylbismuth Reagents
0518
α-Siladifluoromethylation of Lithium Enolates Using TMSCF3
0519
Synthesis of Enantiomerically Enriched Cyclohexanones
0520
ortho-Alkylation and Arylation of Fluoroaryl Imines
0521
C–H Activation of Heterocycles Using an Imine Directing Group
0522
Generation of 3,3-Bis(silyl) Allyloxy Lithium for syn-Addition to Aldehydes and Ketones
0523
Synthesis of Unsymmetric Aryl Aryl Ketones Using Acylindium Reagents
0524
Controlled α- and β-Arylation of Boc-Protected Amines
0525
Copper-Catalyzed α-Amination of Phosphonates and Phosphine Oxides
0526
Synthesis of 2-Substituted 2-Azetines by Lithiation of N-Boc-2-azetines
0527
Reduction of Amides to Alcohols Using SmI2
0528
Direct Trifluoromethylation of Coumarins Mediated by Manganese(III)

Organo- and Biocatalysis

z529
All PDFs of this category
0529
Organocatalytic Asymmetric Formation of Steroids
0530
Kinetic Resolution of BINAM Derivatives Catalyzed by a Brønsted Acid
0531
Proline-Catalyzed Asymmetric N-Nitroso Aldol Reactions
0532
Phase-Transfer-Catalyzed Asymmetric α-Arylation of α-Amino Acid Derivatives
0533
Diels–Alder/Lactonization Cascade Reactions
0534
Asymmetric Cooperative Catalysis in N–H Insertion Reactions
0535
Aminocatalytic Asymmetric Alkylation of Ketones
0536
Isothiourea-Catalyzed Asymmetric [2,3]-Rearrangement of Ylides
0537
Intramolecular Organocatalytic Oxidative Cyclization

Polymer-Supported Synthesis

z539
All PDFs of this category
0539
Hydroboration of Alkynes with Copper Powder
0540
Transamidation of Amides Catalyzed by Fe-Mont
0541
Formylation of Aryl Iodides with CO2 Using Palladium on Carbon
0542
Carbonylative Suzuki–Miyaura Coupling with in situ Generated Pd Nanoparticles
0543
Click Reaction with Cu(II)-Triazine Dendrimer Immobilized on Nanosilica
0544
Asymmetric Hydrogenation of Ketones Using a Fe3O4-Supported Rhodium Complex
0545
Flow Hydration of Nitriles with Manganese Dioxide
0546
A Resin-Bound Phosphoric Acid Catalyst: Asymmetric Flow Reactions
0547
Hydrogenation of Aldehydes Using Phosphine Oxide Stabilized Gold Nanoparticles
0548
Mesoporous Niobium Oxide Sphere Catalyzed Transamidation Reaction
0549
Resin-Bound Triazenes for the Synthesis of Hydrazone Derivatives
0550
Formylation of Amines with DMF Using CeO2

Erratum

0551
Singer, R. A.: Synthesis of Axitinib
0551
Yang, W.; Sun, J.; Xu, X.; Zhang, Q.; Liu, Q.: Synthesis of Benzisoxazolones by Ruthenium and Copper Catalysis
0552
Pace, V.; Rae, J. P.; Procter, D. J.: Copper-Catalyzed Enantioselective 1,4-Conjugate Silyl Additions