DOI: 10.1055/s-00000131

Synfacts

Issue 03 · Volume 11 · March 2015 DOI: 10.1055/s-005-28642

Synform

A33
Zanda, Matteo: SYNFORM ISSUE 2015/03

Synthesis of Natural Products and Potential Drugs

z225
All PDFs of this category
0225
Asymmetric Copper-Catalyzed Hydroamination of Aryl Alkynes
0226
Synthesis of (±)-Hippolachnin A
0227
Synthesis of (+)-Chatancin
0228
Synthesis of ACT-280778
0229
Synthesis of a Histone Deacetylase Inhibitor
0230
Total Synthesis of Alsmaphorazine D
0231
Enantioselective Synthesis of Maoecrystal V
0232
Synthesis of DNA Gyrase Inhibitor
0233
Photochemical Synthesis of Intricarene
0234
Synthesis of Ipatasertib
0235
Synthesis of Zanamivir
0236
Synthesis of (–)-Lundurine A
0237
Formal Synthesis of Hongoquercin B
0238
Synthesis of a Chemokine Receptor Antagonist
0239
Photoredox Catalysis in the Synthesis of JAK2 Inhibitor LY2784544

Synthesis of Heterocycles

z241
All PDFs of this category
0241
Palladium-Catalyzed Synthesis of Isatins from Anilines by Double Carbonylation
0242
Microwave-Assisted Synthesis of Pyrazolotriazines
0243
Multicomponent Synthesis of 3-Arylmethyl-2,5-diarylthiophenes
0244
Benzimidazole-Fused Thiadiazoles From ortho-Phenylenediamine Dithioureas
0245
Preparation of Spirocyclic N-Heterocycles Utilizing Stannyl Amine Reagents
0246
Difluoro-oxindoles by C–H Bond Difluoro-alkylation of Chlorodifluoroacetanilides
0247
Aminoindolines and -indoles by Rhodium-Catalyzed C–H Bond Activation
0248
Synthesis of Fused Pyridines by a ZnCl2-Promoted Three-Component Reaction
0249
Spiro[indene-1,2′-pyrrolidene] by [3+2] Annulation of Pyrroles with Alkynes
0250
Asymmetric Synthesis of Dihydropyridinones and Derivatization
0251
A Hydroheteroarylation Route to 2-Substituted Benzoxazoles
0252
Metal-Free Tandem Oxidative Acylation–Cyclization to Coumarins
0253
6-Trifluoroethylphenanthridines by Photoredox Reaction
0254
Highly Substituted Pyrazoles from N-Propargyl Hydrazones
0255
Indium-Catalyzed Intramolecular Hydroarylation Route to 2H-Chromenes

Synthesis of Materials and Unnatural Products

z257
All PDFs of this category
0257
Truncated π-Helicenes
0258
Semithiobambusurils Binding with Anions and Metal Ions
0259
A Rapid Route to Core Nitrogen Containing Polycyclic Aromatics
0260
Tetraphenylpyrazine-Based Aggregation-Induced Emission Luminogens
0261
Dibenzosiloles by Enantioselective [2+2+2] Cycloaddition
0262
Twisting the π Away
0263
Air on the Side of Naphthyridines
0264
Caught by Copper: Direct Synthesis of Poly(ortho-aryne)s
0265
Annulated Phospholes from Phosphinidenes by C–H Bond Activation
0266
Nothing Boring about this Borylation
0267
Reactivity of Phosphinoboronate Ester
0268
Unforeseen Helicene

Metal-Catalyzed Asymmetric Synthesis and Stereoselective Reactions

z270
All PDFs of this category
0269
Asymmetric Hetero-Diels–Alder Reaction
0270
Palladium-Catalyzed Regio- and Enantioselective C-Alkylation of Isoxazolinones
0271
Rhodium-Catalyzed Asymmetric C–H Functionalization of Methyl Ethers
0272
Asymmetric Hydrogenation of Quinoxalines Catalyzed by Borane
0273
Copper–Bis(NHC)-Catalyzed Asymmetric Conjugate Addition of Dialkylzincs to Enones
0274
Iridium-Catalyzed Asymmetric Allylic Sulfonation
0275
Silver-Catalyzed Asymmetric 1,3-Dipolar Cycloaddition of Azomethine Ylides
0276
A Palladium-Catalyzed Diastereo- and Enantioselective Synthesis of Pyrrolidines
0277
Asymmetric Mannich Reaction of Silyl Ketene Imines with Isatin-Derived Ketimines
0278
Scandium-Catalyzed Asymmetric Homologation of Ketones with α-Diazo Esters
0279
Rhodium-Catalyzed Diastereoselective [3+1+2] Cycloaddition of Aminocyclopropanes
0280
Stereoselective Aminoboration by Means of Copper Catalysis
0281
Cobalt-Catalyzed Enantioselective C–H Alkylation of Indoles
0282
Enantioselective Intramolecular Hydroacylation Catalyzed by Cobalt
0283
Asymmetric Conjugate Addition of Malononitriles to Fluxional Substituted Enoates
0284
Rhodium(III)-Catalyzed C–H Allylation of Benzoic Acid Derivatives
0285
Enantioselective Mannich-Type Reaction of α-CF3 Amide by Copper(I) Catalysis
0286
Copper-Catalyzed Enantioselective Borylation of Aldehydes
0287
Gold-Catalyzed Hydroamination of Alkylidene Cyclopropanes
0288
Desymmetrization of Malonamides via Intramolecular C–N Coupling
0289
Chiral N-Substituted 2-Pyridones via Iridium-Catalyzed Allylic Amination
0290
Synthesis of Spiroindolenines Catalyzed by Palladium
0291
Asymmetric Palladium-Catalyzed Cross-Coupling of Bis(boronates) and Vinyl Halides
0292
Iron-Catalyzed Asymmetric Hydroboration of Styrenes
0293
Iridium-Catalyzed Asymmetric Hydrogenation of Furans and Benzofurans
0294
Enantioselective Alkylation Catalyzed by a Lewis Acid and an Organocatalyst
0295
Enantioselective Synthesis of Piperazin-2-ones and Piperazines
0296
Asymmetric Iridium-Catalyzed Hydrogenation for the Synthesis of Nicotine Analogues
0297
Ester Hydrogenation Promoted Kinetic Resolution of Aliphatic Alcohols
0298
Meyer–Schuster-like Rearrangement of Propargylic Amines

Metal-Mediated Synthesis

z299
All PDFs of this category
0299
Directed Metalation of Ester-Substituted Indolizines
0300
Cobalt-Catalyzed Asymmetric Kumada Cross-Coupling
0301
Zinc-Mediated Alkynylation – Brook Rearrangement – Ene–Allene Cyclization
0302
Copper-Mediated Trifluoromethylation
0303
α-Alkylation of Ketones
0304
Titanate-Mediated Iron-Catalyzed Oxidative Cross-Coupling
0305
Synthesis of Enantiopure Cyclopentenones
0306
Enantioselective Conjugate Addition of Grignard Reagents to Silylated Enoates
0307
Cross-Coupling of Aryllithium Reagents with 2-Alkoxy-Substituted Aryl Chlorides
0308
meta-Selective Arylation of O-β-Naphthyl Carbamate with Boronic Acids
0309
Lithiation–Electrophilic Substitution of tert-Butoxythiocarbonyl Azetidines
0310
Synthesis of Polysubstituted Pyrroles
0311
C-3 Arylation of N-Alkyl-2-pyridones
0312
gem-Difluorinated Nitroso Compounds Derived From Organozinc Reagents
0313
Boron-Catalyzed Reduction of Quinolines

Organo- and Biocatalysis

z315
All PDFs of this category
0315
Isothiourea-Catalyzed Michael Addition to Unsaturated Trichloromethyl Ketones
0316
Enantioselective Phase-Transfer Arylation with Arene Chromium Complexes
0317
NHC-Catalyzed Formal [4+3] and [4+1] Annulations
0318
Organocatalytic Asymmetric Synthesis of 1,2-Dihydronaphthalenes
0319
Phosphinothiourea-Catalyzed Hydroamination of Allenoates
0320
‘Enol Catalysis’ in the Synthesis of Odorants
0321
Mannich-Type Reactions via Chiral Ion Pairs
0322
Enzyme-Catalyzed Cyclopropanation of Aryl-Substituted Olefins
0323
Catalytic Dynamic Kinetic Resolution of β-Halo-α-keto Esters
0324
Alkylative Desymmetrization of Cyclopentane Diones
0325
Enantioselective Intermolecular Cross Rauhut–Currier Reaction
0326
Catalytic Asymmetric Synthesis of Thiols

Polymer-Supported Synthesis

z327
All PDFs of this category
0327
Solid-Phase Synthesis of Phenylalanine-Containing Peptides Using a Triazene Linkage
0328
Flow Oxidation of Alcohols with a Gold Catalyst Under Inductive Heating
0329
MOFs Bearing Free Carboxylic Acids for Organocatalyst Encapsulation
0330
Click Reaction with Copper Nanoparticles Supported on Hexarylbenzene
0331
Magnetically Separable Proton Sponge for Knoevenagel Condensation
0332
Chemoselective Acylation of Primary Alcohols Using [γ-HGeW10O36]7–
0333
Cyanation of Aryl Iodides with K4[Fe(CN)6] Using Pd-BNPs
0334
Synthesis of Substituted Benzoxazoles Using Copper Ferrite Nanoparticles
0335
Iodine-Loaded Ni(II)-MOF Catalyst for Silylcyanation of Benzaldehyde
0336
Synthesis of Ynamides with Copper(I)-Zeolite
0337
Supported Iminophosphorane Superbase Organocatalysts
0338
Synthesis of Benzodiazepines Using Fe3O4@Chitosan
0339
Suzuki Coupling Using a Palladium Catalyst Supported on Carbon-Coated Cobalt NPs
0340
α-Arylation of β-Diketones with Aryl Halides Using CuO/Aluminosilicate
0341
Synthesis of Organozinc Halides and Subsequent Negishi Coupling in Flow

Erratum

0342
Xu, F.; Zacuto, M. J.; Kohmura, Y.; Rosen, J.; Gibb, A.; Alam, M.; Scott, J.; Tschaen, D.: Asymmetric Synthesis of a DPP-4 Inhibitor