DOI: 10.1055/s-00000131

Synfacts

Issue 12 · Volume 13 · December 2017 DOI: 10.1055/s-007-35337

Synform

A194
Zanda, Matteo: SYNFORM ISSUE 2017/12

Synthesis of Natural Products and Potential Drugs

z1225
All PDFs of this category
1225
Synthesis of Actinophyllic Acid
1226
Formal Synthesis of Dendrobine
1227
Synthesis of Raltegravir
1228
Synthesis of (–)-Deoxoapodine
1229
Asymmetric Synthesis of Ipatasertib
1230
Synthesis of (–)-Nahuoic Acid Ci (Bii)
1231
Total Synthesis of Communesin F
1232
Synthesis of (+)-Gracilamine
1233
Synthesis of (–)-Pavidolide B
1234
Asymmetric Transfer Hydrogenation in the Synthesis of Lorlatinib
1235
Synthesis of a 5-Lipoxygenase Activating Protein (FLAP) Inhibitor
1236
Synthesis of a GDC-0994 Intermediate by Kumada–Corriu Cross-Coupling
1237
Enantioselective Synthesis of (2R,6R)-Hydroxynorketamine
1238
Synthesis of BMS-986097

Synthesis of Heterocycles

z1239
All PDFs of this category
1239
Synthesis of β-Lactams through Cyclization of Amide Dianions with Diiodomethane
1240
Multicomponent Coupling Reaction for the Synthesis of Fused Furans
1241
β-Enaminones in the Synthesis of Heterocycles
1242
Visible Light-Mediated Trifluoromethyl Group Installation in Flow
1243
Rhodium-Catalyzed C2-Alkylation of Benzimidazoles
1244
Regioselective Metalation of 1,5-Naphthyridine
1245
Copper-Catalyzed Difluoro- and Perfluoroalkylations of Heterocycles
1246
Palladium-Mediated Synthesis of 3,4-Dihydroisoquinoline N-Oxides
1247
Synthesis of 2-Pyridinimines
1248
Benzannulated Heterocycles by Nucleophilic Amination of Methoxyarenes
1249
Tetrahydropyrans by a Rhodium-Catalyzed Metathesis Cascade
1250
Proline Derivatives through a Radical Redox Strategy
1251
Palladium-Catalyzed Synthesis of 1,2-Disubstituted Azaindole Isomers
1252
trans-Selective Alkynylboration of Alkynes to 4-Alkynyl-1,2-oxaborol-2(5H)-ols

Synthesis of Materials and Unnatural Products

z1253
All PDFs of this category
1253
Reactivity-Enhanced Arene–Metal Complex for the Synthesis of Medium-Sized Rings
1254
Regiospecific Alkynylation Enabled by Ruthenium Catalyst
1255
The Longest Azahelicene, and the Double Thiahelicene
1256
Azulene Gets a Piece of the Pi-Electrons
1257
A Green Method to Blue Fluorophores
1258
Team Up and Get In Gear
1259
An Unexpected Bromide Migration
1260
Stabilizing a neutral π-Radical with Boron
1261
Bend It Like Cyclophanes
1262
A Molecule-Sized Synthetic Robot
1263
B-Doping Shows Positive Results
1264
Bottoms-up to a Doped Nanographene

Metal-Catalyzed Asymmetric Synthesis and Stereoselective Reactions

z1265
All PDFs of this category
1265
Rhodium-Catalyzed cis-Selective Hydrogenation of Fluoroarenes
1266
Asymmetric Synthesis of Vinyltriazenes through [2+2] Cycloaddition
1267
Allylic Alkylation of Nitroallylic Acetates with Acyl Imidazoles
1268
Palladium(0)-Catalyzed C–H Functionalizations of Ketene Aminal Phosphates
1269
Asymmetric Synthesis of Alkynyltetrahydroisoquinolines
1270
Enantioselective Iron-Catalyzed Directed C–H Alkylation
1271
Iridium-Catalyzed Cyclocondensation of Amino Alcohols with Aldehydes
1272
Asymmetric Hydroboration of Geminal Di-substituted Olefins Using a Copper Complex
1273
Stereoselective Lewis Acid Catalyzed Cyclopropyl Carbinol Rearrangement
1274
Iridium-Catalyzed Asymmetric Hydrogenation of Isoquinolines and Pyridines
1275
Asymmetric Hydrogenation by Using a Rhodium–Ferrocenyl Ligand Complex
1276
Chiral Allylic Amines through Palladium-Catalyzed Allylic Substitution
1277
Stereospecific Carbonylative Coupling of Alkyl Tosylates with Dienes
1278
Asymmetric Allylic Alkylation by Synergistic Cu/Pd Catalysis
1279
Cationic Iridium-Catalyzed Intramolecular Asymmetric Hydroaminations
1280
Copper-Catalyzed Enantioselective Arylative Semipinacol Rearrangement
1281
Nucleobases as Nucleophiles in Asymmetric Allylic Amination Reactions
1282
Vanadium-Catalyzed Oxidative Coupling of Phenols and Hydroxycarbazoles
1283
Tandem [3+2] Cycloaddition/1,4-Addition for the Synthesis of Imidazolidines
1284
Asymmetric Synthesis of Isoflavans by Iridium-Catalyzed Hydrogenation
1285
Synthesis of Tetracyclic Indolines by an Asymmetric Tandem Cyclization
1286
Enantioselective Iridium-Catalyzed C–H Amidation of Diaryl Phosphine Oxides
1287
Palladium(0)-Catalyzed Domino Carbene Insertion/Conjugate Addition
1288
Enantioselective Synthesis of Difluoromethyl Cyclopropanes
1289
Scandium-Catalyzed Enantioselective Epoxidation of Electron-Deficient Enynes
1290
cis-Selective Synthesis of 1,2-Disubstituted Carbocycles by Copper-Catalyzed Borylation
1291
Quaternary Substituted Oxindoles through Decarboxylative Asymmetric Allylation
1292
Diastereodivergent α-Allylation of Unprotected α-Hydroxyindanones
1293
Zirconium-Catalyzed Double Carboalumination
1294
Enantioselective Rhodium-Catalyzed Addition to Aldimines

Metal-Mediated Synthesis

z1295
All PDFs of this category
1295
Asymmetric Synthesis of Chiral β-Substituted Amides
1296
Nickel-Catalyzed Biaryl Synthesis Using Polyfluoroaryl Magnesium Reagents
1297
Conversion of Secondary Phosphine Oxides into Tertiary Phosphines
1298
[3+3] Annulation of Vinyl Chromium(0) Carbene Complexes
1299
Negishi Coupling Reactions in Flow with Pd-PEPPSI-IPent-SiO2
1300
Manganese-Catalyzed Ring Opening of Benzofurans
1301
Copper-Catalyzed Three-Component Linchpin Coupling
1302
Preparation of Unsymmetrical 1,2,4,5-Tetrazines
1303
Titanocene-Catalyzed Opening of N-Acylated Aziridines
1304
anti-Selective Carbosilylation of Internal Alkynes
1305
A Zinc-Catalyzed Suzuki–Miyaura Cross-Coupling
1306
Petasis Reaction of Organotrifluoroborates
1307
Nickel-Catalyzed Allylation of Tertiary Alkyl Halides
1308
Tertiary Amine Synthesis with Grignard Reagents
1309
Copper-Catalyzed Borylacylation

Organo- and Biocatalysis

z1311
All PDFs of this category
1311
Photoredox-Catalyzed Hydrocarboxylation of Styrenes in Continuous Flow
1312
Imidodiphosphorimidate-Catalyzed Asymmetric Cycloaddition of Dienes with Aldehydes
1313
Photoredox-Initiated Radical Addition of Alkenes to Carbonyls
1314
Amidation of Carboxylic Acids by Using Carboxylic Acid Reductases
1315
Asymmetric Enzymic Reduction of Structurally Diverse Ketones
1316
Biocatalytic Regioselective para-Carboxylation of Catechols
1317
Organo-Photoredox Catalysis of a Retro-Smiles Rearrangement
1318
Enantioselective Photoreduction of Activated Ketones and Ketimines
1319
Asymmetric Betti/Aza-Michael Sequence
1320
Iterative Catalyst Design for Amino Acid–Thioester Condensation

Polymer-Supported Synthesis

z1321
All PDFs of this category
1321
Direct Amide Condensation by Using Supported Boronates
1322
C–C and C–N Couplings Catalyzed by Copper Nanoparticles in Glycerol
1323
Polystyrene-Supported Phase-Transfer Catalyst for Asymmetric Michael Addition
1324
Synthesis of N-Sulfonylformamidines Catalyzed by an NHC–Copper Complex
1325
Synthesis of Imidazoles, Thiazoles, and Oxazoles by Using Hydrotalcite
1326
Claisen–Schmidt Condensation with Graphene-Supported ZnO Nanoparticles
1327
Metal–Organic Framework Catalyzed Esterification of Carboxylic Acids with Ethers
1328
Hydrodehalogenation with a Chitosan-Supported Cobalt Catalyst
1329
A Pd–Bi–Te/C Catalyst for Aerobic Oxidation of Primary Alcohols
1330
Oxirane Ring Opening on Chitosan–Silica Sulfate Nanohybrid
1331
Cross-Coupling of Organoindiums with Acyl Chlorides on Silicate-Immobilized Palladium
1332
Synthesis of 3-Substituted Indoles Using a Silica-Supported Vanadium Catalyst
1333
Selective Reduction of Azines to Hydrazones on Supported Silver Nanoparticles
1334
Phosphonium Salt Catalyzed Cycloaddition of Epoxides with Carbon Dioxide
1335
Synthesis of Benzofurans and Indoles by Using Supported Palladium Nanoparticles
1336
Nickel–Rhenium/Titania Catalysts for Hydrogenation of Aliphatic Esters to Alcohols

Erratum

1337
Zhao, Y.; Chen, Y.; Newhouse, T. R.: Palladium-Catalyzed α,β-Dehydrogenation of Carboxylic Acids