DOI: 10.1055/s-00000131

Synfacts

Issue 04 · Volume 14 · April 2018 DOI: 10.1055/s-008-39405

Synform

A47
Zanda, Matteo: SYNFORM ISSUE 2018/04

Synthesis of Natural Products and Potential Drugs

z0331
All PDFs of this category
0331
Synthesis of Aminocyclohexenes from 7-Azanorbornenes
0332
Synthesis of Canagliflozin
0333
Syntheses of Plakortin Polyketides
0334
Enantioselective Total Synthesis of (–)-α-Cyclopiazonic Acid
0335
Synthesis of Histone Acetyltransferase Inhibitor A-485
0336
Synthesis of Δ9-Tetrahydrocannabinol
0337
Synthesis of (+)-Pleuromutilin
0338
Synthesis of BMS-986118
0339
Synthesis of Arboridinine
0340
Synthesis of PF-06815189
0341
Total Syntheses of Stephacidin Congeners
0342
Modular Synthesis of Bisquinolizidine Alkaloids
0343
Asymmetric Alkynylation in the Synthesis of Efavirenz Intermediates
0344
Enantioselective Synthesis of (+)-Astellatol
0345
Synthesis of M-525

Synthesis of Heterocycles

z0347
All PDFs of this category
0347
Cooperative Amine–Copper Catalysis
0348
Gold-Catalyzed Synthesis of Isoxazole-Fused Heterocycles
0349
Benzannulated Heterocycles by Aza-Claisen Rearrangement
0350
Palladium-Catalyzed Amination of Chloroheteroarenes with Secondary Amines
0351
Dehydrogenative Cyclization of 8-Amido-quinolines
0352
Minisci Alkylation of Heteroarenes with Boronic Acids
0353
Catalytic Pummerer Reaction Approach to 3-Thiofurans and 3-Thiobenzofurans
0354
Synthesis of γ-Lactams by Radical-Induced 1,6-Enyne Cyclization
0355
3,4-Dihydroisoquinolines by Photooxidative Annulation of Imines with Alkenes
0356
α-Functionalization of Unprotected Cyclic Amines by Hydride Abstraction
0357
Facile Access to Dihydrocoumarins through Catalytic Hydroarylation
0358
Electrochemical Synthesis of Imidazo-Fused Heterocycles
0359
Tetrahydropyridines from Condensation of Sulfonamidoenones with N-Sulfonylimines
0360
Synthesis of Spirocyclic Pyrido- and Pyrroloquinolines from an Isatin Derivative

Synthesis of Materials and Unnatural Products

z0361
All PDFs of this category
0361
Chemical Cubism: Cubanes Cross-Coupled to Chromophores and More
0362
Heterocyclic Fluorophores via Grignard Chemistry
0363
Annulative Dimerization of Chloroarenes Gives Fused Aromatics
0364
Facile, Mild Access to Polydiquinolineanthracene
0365
Green and Gold: Au Catalysis Improves Iododeboronation Scope
0366
Rotaxane Polymer Shines under Stress
0367
Luminescent Polymers Know Self-Defense
0368
Dual Vicinal Functionalization Cascade of Indoles
0369
Synthesis of Disubstituted Dihydrofuran-Fused Fullerenes
0370
π-Extension Through the Catellani Reaction
0371
Synthesis of Fused Nanohoops
0372
Adding Space and Dimension to Tetrathiafulvalenes

Metal-Catalyzed Asymmetric Synthesis and Stereoselective Reactions

z0373
All PDFs of this category
0373
Iridium-Catalyzed Regio- and Enantioselective Amination
0374
Manganese-Catalyzed Oxidative Kinetic Resolution of Heterocyclic Sulfoxides
0375
Tetrahydrofuroindoles by a Palladium-Catalyzed Asymmetric Dearomatization
0376
AgSbF6-Catalyzed Tandem Rearrangement/Friedel–Crafts Alkylation
0377
Regioselective Silylation: Synthesis of 1,2-Diols
0378
Regioselective Silylation: Synthesis of 1,4-Diols
0379
Stereodivergent Allylation of Azaaryl Acetamides/Acetates
0380
Asymmetric Alkynylation of Ketimines
0381
The First Useful Planar Chiral dbCOT-Ligands
0382
Enantioselective Copper-Catalyzed Mannich-Type Reaction
0383
Enantioselective Direct Aldol Reaction of α-Vinylated Thioamides
0384
Rhodium-Catalyzed Hydrogenation–Desymmetrization of Cyclohexadienones
0385
Zinc-Catalyzed Synthesis of 8-Oxabicyclo-[3.2.1]octanes
0386
Asymmetric Perfluoroalkylation of β-Keto Esters by Nickel/Photoredox Catalysis
0387
Copper-Catalyzed Enantioselective Allylation of Ketones
0388
Rhodium-Catalyzed Asymmetric Enyne Cycloisomerization
0389
Palladium-Catalyzed Asymmetric Synthesis of Oxazolines
0390
Asymmetric Hydrogenation of Amino-containing Phenanthrenes
0391
Cooperative Effect Ensures Efficient Aza-Wacker Reaction
0392
α-Arylation of Cyclobutanones through Synergistic Palladium/Enamine Catalysis
0393
Asymmetric Synthesis of α-Substituted α-Amino Acids and α-Amino Amides
0394
Regio- and Diastereoselective Synthesis of Isoxazolidines
0395
Cycloaddition of Azomethine Ylides with Benzo[b]thiophene Sulfones
0396
Iridium-Catalyzed Enantioselective Reduction of Heteroaryl Ketones
0397
Palladium-Catalyzed Formal [3+2] Annulation
0398
Palladium-Catalyzed Enantioselective Cycloaddition of Vinyloxetanes
0399
‘Chiral-at-Metal’ Asymmetric Conjugate Addition of 2-Acylimidazoles
0400
Manganese-Catalyzed Selective Hydrosilylation of Alkynes
0401
Enantioselective Copper-Catalyzed Borylation–Addition to Fluoroalkyl Ketones
0402
P-Stereogenic Products by Hydroarylation of Divinylphosphine Oxides

Metal-Mediated Synthesis

z0403
All PDFs of this category
0403
Dual Photoredox/Nickel-Catalysis for the Cross-coupling of Aziridines
0404
Amide Synthesis Using Ynones as Acylation Agents
0405
Addition of Lithiated Dithianes to the Autoxidized Counterpart
0406
Construction of Quinazolines via Iron-Catalyzed Amination
0407
Diastereoselective Synthesis of Alkenyl Boronates
0408
Mn(II)Cl2-Catalyzed Stille Cross-Couplings
0409
Regioselective Hydroboration of Aryl Alkenes
0410
Nickel-Catalyzed Synthesis of 3,3-Disubstituted Oxindoles
0411
Highly Efficient Barbier–Negishi Coupling of Secondary Alkyl Bromides
0412
New Photoinduced Meerwein-Type Arylation
0413
α,β-Dehydrogenation of Cyclic Ketones
0414
Bench-Stable Solid Triorganoindium Reagents
0415
Radical Polar Crossover Reaction of Vinyl Boron Ate Complexes
0416
Inert C–O Bond Functionalization Using an Organo Rare-Earth Metal Complex
0417
Difluoroalkylation and Trifluoromethylchalcogenation

Organo- and Biocatalysis

z0419
All PDFs of this category
0419
Chemoenzymatic Distal C–H Hydroxylation
0420
Supramolecular Brønsted Acid Catalyzed Carbonyl–Olefin Metathesis
0421
Phosphine Oxide-Catalyzed γ-Umpolung Addition–Wittig Olefination
0422
Sulfide-Catalyzed Cross-Coupling of Benzyl Halides and Boronic Acids
0423
Purine Nucleoside Synthesis by Three-Component Dynamic Kinetic Resolution
0424
β-Alkylation of Enals by Excited-State Iminium Catalysis
0425
Site-Selective Oxidation of Macrolactones with a Single Biocatalyst
0426
Construction of Halogenated Quaternary Carbon Centers
0427
Bisguanidinium-Controlled Asymmetric Rearrangements of Acylsilanes
0428
Desymmetrizing Asymmetric Selenoetherification

Polymer-Supported Synthesis

z0429
All PDFs of this category
0429
Racemization of Tertiary Alcohols on Acidic Resins
0430
Reduction of Nitroarenes on Palladium/Nickel-Doped Iron Nanoparticles
0431
Suzuki–Miyaura Reaction Catalyzed by Cage-Templated Palladium Nanoparticles
0432
One-Pot Aza-Friedel–Crafts Reaction on Amberlyst 15-Supported Silicotungstic Acid
0433
Heterobimetallic Catalysis: Access to Trifluormethylated vic-Amino Alcohols
0434
Hydrolysis of BH3·NH3 and Synthesis of Quina-zolines Catalyzed by Ni–Pd Nanoparticles
0435
Mesoporous Polymer Supported Gold(I) Catalysts
0436
Photocatalyzed Reduction of Azides to Amines
0437
An Imidazolium-Functionalized Metal–Organic Framework for Fixation of CO2
0438
Suzuki–Miyaura Cross-Coupling on a Palladium/Melamine–Cyanurate Catalyst
0439
C–H Acylation of Phenylpyrazoles on Kaolin-Supported Palladium Nanoparticles
0440
Cu(II) Metal–Organic Framework Catalyst for Cycloaddition of CO2 to Epoxides
0441
Synthesis of Triazole[1,2-a]indazoletriones on Silica-Coated Zinc Oxide
0442
Huisgen Cycloaddition Catalyzed by Hydro-talcite-Supported Copper Nanoparticles
0443
Supported Cobalt Nanoparticles for Catalytic Reduction of Aldehydes by Formic Acid