DOI: 10.1055/s-00000131

Synfacts

Issue 09 · Volume 14 · September 2018 DOI: 10.1055/s-008-41137

Synform

A135
Zanda, Matteo: SYNFORM ISSUE 2018/09

Synthesis of Natural Products and Potential Drugs

z0885
All PDFs of this category
0885
Synthesis of a Bruton’s Tyrosine Kinase Inhibitor
0886
Synthesis of Sofosbuvir
0887
Total Synthesis of (±)-Salimabromide
0888
Synthesis of (+)-Mangrolide A
0889
Flow Synthesis of Dolutegravir
0890
Total Synthesis of (±)-Cossonidine
0891
Total Synthesis of (–)-Halenaquinone
0892
Synthesis of Δ12-Prostaglandin J3
0893
Total Synthesis of (–)-Insulicolide A
0894
Total Synthesis of Gelsemium-Type Alkaloids
0895
Synthesis of MK-7622
0896
Synthesis of 5-Fluoro-1,3-oxazine β-Secretase Inhibitors
0897
Synthesis of 1,3-Oxazine Based β-Secretase Inhibitors
0898
Total Synthesis of (±)-Stephadiamine
0899
Synthesis of PF-06409577
0900
Synthesis of Nelfinavir
0901
Synthesis of Latanoprost

Synthesis of Heterocycles

z0903
All PDFs of this category
0903
Flow Photochemical Synthesis of Bicyclic Aziridines from Pyridinium Salts
0904
Synergistic Catalysis: Enhanced Regio-selectivity in the Synthesis of 1,2,3-Triazoles
0905
Azaheterocycles by Ring-Closing Metathesis of Enynamides
0906
Transition-Metal-Free Synthesis of 3-Carbonylated Benzofurans
0907
Asymmetric Synthesis of 5,6-Dihydropyran-2-ones
0908
N-Heterocyclic Carbene Catalyzed Enantio-selective Synthesis of 1,5-Benzodiazepines
0909
Synthesis of Functionalized Heteroaromatics from ortho-Ester Protected Pyruvates
0910
Visible-Light-Mediated Synthesis of Trifluoromethylated Coumarins
0911
Synthesis of 2,5-trans-Tetrahydrofuran-2-ylacetonitriles
0912
Cs2CO3-Mediated Synthesis of 2,3-Diaryl-2H-azirines from Ketoxime Acetates
0913
Manganese-Catalyzed Synthesis of peri-Condensed Heterocycles
0914
3-Acylisoquinolines by Cobalt-Catalyzed Annulation of Benzohydrazides
0915
Indolines by Rhodium(III)-Catalyzed Annulation of 2-Alkenylanilides with Alkynes
0916
Carbene-Mediated Benzodioxole Synthesis

Synthesis of Materials and Unnatural Products

z0917
All PDFs of this category
0917
You’ve Got to Picket a Pocket or Two
0918
The Consequences of Adding a Twist to Acenes
0919
Polycyclic Aromatic Hydrocarbon with Embedded Azulene Unit
0920
Porphyrin Dimers Undergo Forbidden Dimerization
0921
Fluorescent 1,3-Azaphospholes with Pyrrolo[1,2-a]quinoline Skeletons
0922
A Stable Peri-tetracene Diradicaloid
0923
Fullerenes Full of Arenes
0924
One-Pot Synthesis of Carborane-Fused N-Polyheterocycles
0925
PEGose: A Synthetic Polymer with Stereocontrolled Cyclic Architecture
0926
A Practical Preparation of Olefin Triblock Copolymers
0927
π-Conjugated Macrocyclic Receptor Featuring Redox-Active Viologen Units
0928
BINOL, I Think He’s Got It! Direct Functionalization of 9-Methoxyphenanthrene

Metal-Catalyzed Asymmetric Synthesis and Stereoselective Reactions

z0929
All PDFs of this category
0929
Asymmetric Copper-Catalyzed Defluoroalkylation
0930
Rh-Catalyzed Enantioselective Synthesis of Trifluoromethylcyclopropanes
0931
Palladium-Catalyzed Enantioselective C(sp3)–H Fluorination
0932
Palladium-Catalyzed Enantioselective meta-C(sp2)–H Activation
0933
Copper-Catalyzed Dearomative Borylation of Indoles
0934
Asymmetric Intramolecular Hydroarylation of Allyl Aryl Ethers
0935
Copper-Catalyzed Asymmetric Synthesis of 3-Azabicyclo[3.1.0]hexane Scaffolds
0936
Enantioselective [3+2] Cycloadditions of β-Silylacrylates
0937
Palladium-Catalyzed Atropo-Enantioselective C–H Functionalization
0938
Copper-Catalyzed Asymmetric Synthesis of Homoallylic Alcohols via Borylation
0939
Diastereoselective Cu-Catalyzed Synthesis of 1,2-anti-Difunctionalized Cyclopropanes
0940
Palladium-Catalyzed Stereoselective Synthesis of 1,4-Dienes
0941
Iridium-Catalyzed Enantioselective Allylic Alkylation
0942
Rh-Catalyzed Cycloaddition of 2-Acyl imidazoles and Azomethine Imines
0943
Rhodium-Catalyzed Enantioselective Synthesis of α-Tertiary Amino Acids
0944
Copper-Catalyzed Enantioselective Synthesis of Tetrahydroquinazolines
0945
Rh-Catalyzed Cycloaddition of Vinylindoles to Vinyl(diazo)acetates
0946
Asymmetric Rhodium-Catalyzed Synthesis of Geminal Dicarboxylates
0947
Enantioselective Synthesis of Diarylmethyl-phosphonates
0948
Asymmetric Synthesis of 2-Substituted 2,3-Dihydro-1,4-benzodioxanes
0949
Dynamic Kinetic Resolution of Allylic Bromides
0950
Enantioselective [8+3] of meso-Aziridines with Tropones or Azaheptafulvenes
0951
Asymmetric Aminoacetoxylation of Nonactivated Alkenes by Palladium Catalysis
0952
Ni-Catalyzed Tandem Metallacyclization/Cross-Electrophile Coupling
0953
Copper-Catalyzed Stereodivergent Synthesis of α,β-Dibranched γ-Boryl Amines
0954
Copper-Catalyzed Diastereoselective A3-Coupling Reaction
0955
Diastereoselective Reductive Arylation of Internal Alkynes
0956
Access to trans-Disilylated Enones using Rhodium Catalysis
0957
Gold/Rhodium-Catalyzed Enantioselective Cycloaddition
0958
(E)-Selective Hydrosilylation of Terminal Alkynes by Cobalt Catalysis

Metal-Mediated Synthesis

z0959
All PDFs of this category
0959
Enantiodivergent Allene Synthesis
0960
Mono- and Difluorination and Trifluoromethylthiolation of Heterobenzylic Scaffolds
0961
Asymmetric Allylic Substitution of Dibromocycloalkenes
0962
Reductive Transamidation of Tertiary Amides via Manganese Metal
0963
Iron-Catalyzed Cross-Coupling of Alkenyllithium with Vinyl Halides
0964
Nickel-Catalyzed Diarylation of Unactivated Olefins
0965
Photocatalytic Cyclopropanation of CF3-Substituted Olefins and other Alkenes
0966
Manganese-Catalyzed Olefination of Methyl-Substituted Heteroarenes
0967
Nickel-Catalyzed Branch-Selective Alkylation of Aryl Fluorides
0968
Nickel-Catalyzed Three-Component Hydroperfluoroarylation of 1,3-Dienes
0969
Diastereoselective Fluorination and Subsequent Epimerization Reaction
0970
Diastereoselective α,α-Bisalkylation of Chiral Methyl Ketones
0971
Zinc-Mediated Silylmetalation of Terminal Alkynes
0972
Nickel-Catalyzed Remote Functionalization of Unsaturated Ethers
0973
An Ammonia-Free Birch Reduction with a Simple Experimental Procedure

Organo- and Biocatalysis

z0975
All PDFs of this category
0975
Carbonyl-Catalyzed Biomimetic Asymmetric Mannich Reaction
0976
Cooperative Lewis Base–Lewis Acid Catalysis for Iodochlorination of Alkenes
0977
Asymmetric Photo-Organocatalytic C–H Functionalization of Toluene Derivatives
0978
Proline-Catalyzed Asymmetric Inverse Electron Demand Diels–Alder Reaction
0979
Chemo-Enzymatic Total Synthesis of Sorbicillinoids
0980
α-Chiral Azahetaryl Ethylamines through Asymmetric Protonation
0981
Unnatural Reactivity Enabled by Photoredox Catalysis in Oxidoreductases
0982
An Alternative Mechanism for ‘Iminium-Ion’ Catalysis
0983
Enantioselective Synthesis of Cyclopentenes via β-Azolium Ylides
0984
Design of a Bifunctional Photoaminocatalyst for the Alkylation of Aldehydes

Polymer-Supported Synthesis

z0985
All PDFs of this category
0985
Synthesis of Aurones from Chalcones on Pd-on-Au Bimetallic Nanoparticles
0986
Transfer Hydrogenation on Polystyrene-Supported Rhodium Nanoparticles
0987
Palladium/Carbon-Catalyzed Flow C–H Functionalization of 1,2,3-Triazoles
0988
Platinum-Catalyzed Deuteration of Acrylic and Methacrylic Acid Derivatives
0989
Continuous-Flow Oxidation of Alcohols on Graft-Copolymer-Supported TEMPO
0990
Olefin Metathesis Catalyzed by a Carboxyl Graphene-Supported Ruthenium Complex
0991
C–H Allylation of Thiophenes on Graphene Oxide
0992
C–C Bond Formation Catalyzed by Palladium/Copper Ferrite Nanowires
0993
Synthesis of Propargylamines on Supported Silver Nanoparticles
0994
Ullmann Coupling with Mesoporous-Carbon-Supported Au–Pd Bimetallic Nanoparticles
0995
Click Reaction Catalyzed by a One-Dimensional Copper(I) Coordination Polymer
0996
Transfer Hydrogenation of Nitroarenes with B,N-Co-Doped Carbon Materials
0997
Solid-Phase Submonomer Synthesis of α-Alkyl-β-Peptoids