DOI: 10.1055/s-00000131

Synfacts

Issue 06 · Volume 15 · June 2019 DOI: 10.1055/s-009-43102

Synform

A78
Zanda, Matteo: SYNFORM ISSUE 2019/06

Synthesis of Natural Products and Potential Drugs

z0581
All PDFs of this category
0581
Enantioselective Total Synthesis of (–)-Ambiguine
0582
Total Synthesis of (–)-Alstofolinine A
0583
Formal Synthesis of Entecavir
0584
Synthesis of (–)-Oxycodone
0585
Syntheses of (+)-Akuammiline and (–)-Echitamine
0586
Syntheses of (–)-Indoxamycins A and B
0587
Synthesis of (±)-Chalcitrin
0588
Synthesis of Cembrane Diterpenoids
0589
Total Synthesis of Endiandric Acids

Synthesis of Heterocycles

z0591
All PDFs of this category
0591
Electrochemical Reduction of Arenes
0592
CuH-Mediated Regiodivergent Synthesis of Chiral Alkylated Indoles
0593
Enantioselective Synthesis of Pentacyclic Spirooxindoles
0594
Synthesis of γ-Arylated Butenolides by Palladium or Copper Catalysis
0595
A C–H Bond Alkenylation/Aza-Michael Route to Benzoisothiazole 1-Oxides
0596
Synthesis of Substituted Benzimidazoles by C–H Imination
0597
Nitrene C–H Bond Insertion Strategy for Synthesis of γ-Lactams
0598
Photoredox Radical/Polar Crossover Synthesis of Nitrogen Heterocycles
0599
Synthesis of α- and β-C-Glycosyl Arenes by Direct Iridium-Catalyzed Hydroarylation
0600
Cobalt-Catalyzed Synthesis of Isoquinolines by Using a Traceless Directing Group
0601
Intramolecular Radical Cyclization of 2-Azaallyls to Benzofuran Derivatives
0602
Rhodium(II)-Catalyzed Enantioselective Synthesis of N-Substituted 2-Pyridones
0603
Hexahydro-1H-cyclopenta[c]pyrazolo[1,2-a]pyrazole-1,5(2H)-diones
0604
9a,10,12,12a-Tetrahydrobenzo[b]cyclopenta[f]pyrrolo[1,2-d][1,4]diazepinones

Synthesis of Materials and Unnatural Products

z0605
All PDFs of this category
0605
Everything’s Greener on the Other Graphene
0606
It Takes a Pretty Copper to Cyclize
0607
A Modular Approach to Acridinium Photocatalysts
0608
Ligand-Controlled DArP for n-Type and Ambipolar Mesopolymers
0609
A New Coupling Partner for Selective Aromatic Functionalization
0610
Acid-Mediated Synthesis of Substituted Dibenzo- and Dithienoacridines
0611
Modding Off: Modular Synthesis of 2-Aryl Triazoles Yields Mechanochromic Luminescence
0612
Singlet Biradical Character in a Polycyclic Zwitterion
0613
Cook Me and Call Me the Molecular Dice!
0614
Phospholes to Phos-bowls: The First Synthesis of Phosphindolizine Analogues
0615
Phenol-Yne Polymerization
0616
[2+1+2+1] Cycloaddition for Fused Unsymmetric Naphthalenes

Metals in Synthesis

z0617
All PDFs of this category
0617
Copper-Catalyzed Alkyne–Azide Cycloaddition by Kinetic Resolution
0618
α-Alkylation of β,γ-Unsaturated Carboxylic Acids with Chiral Lithium Amides
0619
Asymmetric C–H Functionalization Using Chiral CpxCo(III) Catalysis
0620
The Directed Metalation Group Dance
0621
C–H Activation/Diels–Alder/retro-Diels–Alder Cascade
0622
Photocatalyzed Uranyl C–C Bond Formation
0623
Nickel-Catalyzed C–O Bond Arylation of Oxalates
0624
Chemoselective sp3-C–H Activation in Oxidative Coupling to Form Quaternary Centers
0625
Divergent Additions of N-tert-Butanesulfinylimidates to Acylsilanes
0626
Chromium-Catalyzed Amidation of Esters
0627
Synthesis of Azetidines via Strain Release
0628
‘Frustrated’ Acid/Base Catalyzed Conia-Ene-Type Cyclizations
0629
Nickel-Catalyzed Nucleophilic Amination of (Hetero)aryl Chlorides
0630
Photoredox/Diarylborinic Acid Catalyzed Selective C–H Alkylation of Carbohydrates
0631
Penta-Alkenylated Carboboranes through Cross-Coupling of Monocarboranes with Alkenes
0632
Isomerization of Alkenes by Dual-Visible-Light-Cobalt Catalysis
0633
Carbonyl–Carbonyl Metathesis via Photoredox Catalysis
0634
Enantioselective Benzylic Arylation of C–H Bonds
0635
Amine Arylation via C–F Bond Activation
0636
Photocatalytic Alkylation of Heteroarenes
0637
α-Arylation of Ketones
0638
Copper-Catalyzed Synthesis of Chiral Tertiary Alcohols from 1,3-Dienes and Ketones
0639
Iridium-Catalyzed C–C Activation Driven by Aromatization
0640
α,β-Dehydrogenation and Oxidative Cycloalkenylation Catalyzed by Nickel
0641
Iron-Catalyzed Alkenylation of Organomagnesium Reagents
0642
Enantioselective Bimetallic Synthesis of 6,6-Spiroketals
0643
Rhodium-Catalyzed Asymmetric Hydroarylation of Chromenes
0644
Preparation of β-Fluoroalkyl β-Amino Acids
0645
An Unprecedented C(aryl)–CH3 Bond Cleavage

Polymer-Supported Synthesis

z0647
All PDFs of this category
0647
Cobalt Molybdenum Sulfide-Catalyzed S-Alkylation of Thiols or H2S with Alcohols
0648
Microporous Supported Platinum Catalyst for Suzuki–Miyaura and Heck Reactions
0649
Platinum-Catalyzed Reductive Amination of Levulinic Acid To Give Pyrrolidones
0650
Aziridation of Olefins Catalyzed by Copper Immobilized on Magnetic Nanoparticles
0651
Cyclization of Diamines with Aldehydes on a Nanoparticulate Cobalt Catalyst
0652
Nanoparticulate-Nickel-Catalyzed Reductive Amination of Carbonyl Compounds
0653
Silicone-Coated Palladium or Platinum Hydrogenation Catalysts
0654
Hydrosilylation of Alkenes Catalyzed by Nickel Carboxylate Metal–Organic Frameworks
0655
Metal–Organic Framework Catalyst for Knoevenagel Condensations
0656
Metal–Organic Framework Catalyst for Nozaki–Hiyama Allenylations
0657
Oxidation of Benzylic Alcohols on Nitrogen and Phosphorus Co-Doped Graphene
0658
Hydroxylation of Oxime Ethers with Binaphthyl-Stabilized Palladium Nanoparticles
0659
Palladium-Catalyzed Aminocarbonylation of Iodobenzenes
0660
Synthesis of Benzo[a]pyrano[2,3-c]phenazines on Sulfonated Graphene Oxide

Organo- and Biocatalysis

z0661
All PDFs of this category
0661
Valorization of a Saturated Fatty Acid to Enantioenriched (S)-δ-Decalactone
0662
Organocatalytic Asymmetric Hydroamination of Allenes and Dienes
0663
Biosynthesis of Streptoseomycin Involves a [6+4] Cycloaddition
0664
Amination of Sugars and Sugar-Derived Tetrahydrofurans with Transaminases
0665
Organocatalytic Synthesis of Unsymmetrical 1,2,4,5-Tetrazines
0666
Halogen Bond Catalyzed Strain-Release Glycosylation
0667
Biocatalytic Synthesis of d-Tryptophans from Indoles
0668
Enantioselective Radical Addition to Vinylpyridines by Photoredox Catalysis
0669
The Shi Epoxidation

Chemistry in Medicine and Biology

z0671
All PDFs of this category
0671
LYTACs for the Degradation of Secreted and Membrane Proteins
0672
Design and Synthesis of a Selective CDK7 Covalent Inhibitor
0673
Discovery of New Chemotypes by Deep Screening of an Ultra-large Virtual Library
0674
Prebiotic Link between RNA and DNA
0675
Late-Stage Negishi Coupling of Peptides
0676
A Highly Selective and Potent Small-Molecule Inhibitor of Factor B
0677
A Far-Red Emitting IrIII-Complex–Coumarin Dyad for Photodynamic Therapy
0678
Dual Inhibitors of Anaplastic Lymphoma Kinase and Bromodomain‑4
0679
Clickable FPP/GGPP Analogues Enable Analysis of Prenylome
0680
Modification of Phosphinopeptidic Scaffolds by Giese-Type Alkylation
0681
Development of Fluorescent Ca2+ Sensors

Peptide Chemistry

z0683
All PDFs of this category
0683
Amide N–H Arylation of Pyroglutamate–Histidine Promoted by Nickel(II) Acetate
0684
Oligomerization of Amino Thioacids by Simple Oxidation
0685
Palladium-Catalyzed Site-Selective γ-C(sp3)–H Silylation of Peptides
0686
Ruthenium-Catalyzed Dynamic Kinetic Resolution–Asymmetric Hydrogenation
0687
One-Pot Reaction of Amino Acid Esters with Isocyanates and α-Bromo Ketones
0688
Palladium-Catalyzed Insertion of Carbenoids into N,O-Aminals
0689
Synthesis of the C-Terminal Macrocycle of Asperipin-2a
0690
Peptide Ligation Mediated by a Removable Acyl Transfer Auxiliary
0691
Thiourea/Boronic Acid Catalyzed Asymmetric Aza-Michael Reaction
0692
Silver(I)-Promoted Macrocyclization of Linear Peptides

Flow Chemistry

z0693
All PDFs of this category
0693
Light-Induced Beckmann Rearrangement in Continuous Flow
0694
Continuous-Flow Friedel–Crafts Acylation by Zirconium–β-Zeolite Catalysis
0695
Aldol Condensation Catalyzed by an Immobilized Base in Continuous Flow
0696
An Immobilized Palladium Catalyst for Cross-Couplings in Continuous Flow
0697
Gas/Liquid-Phase Microflow Trifluoromethylation with Fluoroform

Erratum

0698
Xie, J; Sekine, K; Witzel, S; Krämer, P; Rudolph, M; Rominger, F; Hashmi, A S. K: Photochemical Gold-Catalyzed Arylations