Myasthenia gravis – Schritt für Schritt

Die Myasthenia gravis wird durch eine autoantikörpervermittelte Übertragungsstörung an der neuromuskulären Endplatte hervorgerufen. Leitsymptom ist eine belastungsabhängige Muskelschwäche. Diagnostisch haben der Nachweis von typischen Autoantikörpern und die elektrophysiologische Untersuchung einen hohen Stellenwert. Symptomatische und immunmodulierende medikamentöse Therapien stehen zur Verfügung, für bestimmte Patienten auch die Thymektomie. Die Prognose wird durch myasthene Krisen bestimmt, die mit einer erhöhten Mortalität einhergehen.

Publication History

Article published online:
05 March 2024

• Literatur

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