Semin Plast Surg 2010; 24(3): 237-254
DOI: 10.1055/s-0030-1263066
© Thieme Medical Publishers

Perforator Flaps in Head and Neck Reconstruction

Jagdeep S. Chana1 , Joy Odili1
  • 1Department of Plastic and Reconstructive Surgery, Mount Vernon Hospital, Northwood, Middlesex, United Kingdom
Further Information

Publication History

Publication Date:
20 August 2010 (online)

ABSTRACT

Free tissue transfer has revolutionized the management of complex head and neck defects. Perforator flaps represent the most recent advance in the development of free flap surgery. These flaps are based on perforating vessels and can be harvested without significant damage to associated muscles, thereby reducing the postoperative morbidity associated with muscle-based flaps. Elevation of perforator flaps requires meticulous technique and can be more challenging than raising muscle-based flaps. Use of a Doppler device enables reliable identification of the perforating vessels and aids in the design of free-style free flaps, where the flaps are designed purely according to the perforator located. The major advantage of free-style free flaps is that an unlimited number of flaps can potentially be designed on much shorter pedicles. The anterolateral thigh flap is the most commonly used perforator flap in head and neck reconstruction. Its use is described in detail, as is use of other less common perforator flaps. This article also describes head and neck reconstruction in a region-specific manner and gives a short-list of suitable flaps based on the location of the defect.

REFERENCES

  • 1 Ariyan S. The pectoralis major myocutaneous flap. A versatile flap for reconstruction in the head and neck.  Plast Reconstr Surg. 1979;  63 73-81
  • 2 Bakamjian V Y. A two-stage method for pharyngoesophageal reconstruction with a primary pectoral skin flap.  Plast Reconstr Surg. 1965;  36 173-184
  • 3 Owens N. A compound neck pedicle designed for the repair of massive facial defects: formation, development and application.  Plast Reconstr Surg. 1955;  15 369-389
  • 4 Seidenberg B, Rosenak S S, Hurwitt E S, Som M L. Immediate reconstruction of the cervical esophagus by a revascularized isolated jejunal segment.  Ann Surg. 1959;  149 162-171
  • 5 Soutar D S, Scheker L R, Tanner N S, McGregor I A. The radial forearm flap: a versatile method for intra-oral reconstruction.  Br J Plast Surg. 1983;  36 1-8
  • 6 Hidalgo D A. Fibula free flap: a new method of mandible reconstruction.  Plast Reconstr Surg. 1989;  84 71-79
  • 7 Taylor G I. The angiosomes of the body and their supply to perforator flaps.  Clin Plast Surg. 2003;  30 331-342, v v
  • 8 Kroll S S, Reece G P, Miller M J et al.. Comparison of cost for DIEP and free TRAM flap breast reconstructions.  Plast Reconstr Surg. 2001;  107 1413-1416 discussion 1417-1418
  • 9 Gedebou T M, Wei F C, Lin C H. Clinical experience of 1284 free anterolateral thigh flaps.  Handchir Mikrochir Plast Chir. 2002;  34 239-244
  • 10 Allen R J, Treece P. Deep inferior epigastric perforator flap for breast reconstruction.  Ann Plast Surg. 1994;  32 32-38
  • 11 Koshima I, Moriguchi T, Soeda S, Kawata S, Ohta S, Ikeda A. The gluteal perforator-based flap for repair of sacral pressure sores.  Plast Reconstr Surg. 1993;  91 678-683
  • 12 Angrigiani C, Grilli D, Siebert J. Latissimus dorsi musculocutaneous flap without muscle.  Plast Reconstr Surg. 1995;  96 1608-1614
  • 13 Wei F C, Jain V, Suominen S, Chen H C. Confusion among perforator flaps: what is a true perforator flap?.  Plast Reconstr Surg. 2001;  107 874-876
  • 14 Blondeel P N, Beyens G, Verhaeghe R et al.. Doppler flowmetry in the planning of perforator flaps.  Br J Plast Surg. 1998;  51 202-209
  • 15 Taylor G I, Caddy C M, Watterson P A, Crock J G. The venous territories (venosomes) of the human body: experimental study and clinical implications.  Plast Reconstr Surg. 1990;  86 185-213
  • 16 Mardini S, Tsai F C, Wei F C. The thigh as a model for free style free flaps.  Clin Plast Surg. 2003;  30 473-480
  • 17 Song R, Yang P, Liu J. Reconstruction of the cheek and lips.  Clin Plast Surg. 1982;  9 71-72
  • 18 Timmons M J, Poole M D. Reconstructive surgery in the treatment of intraoral cancer.  Br J Oral Maxillofac Surg. 1986;  24 77-85
  • 19 Blondeel N, Vanderstraeten G G, Monstrey S J et al.. The donor site morbidity of free DIEP flaps and free TRAM flaps for breast reconstruction.  Br J Plast Surg. 1997;  50 322-330
  • 20 Song Y G, Chen G Z, Song Y L. The free thigh flap: a new free flap concept based on the septocutaneous artery.  Br J Plast Surg. 1984;  37 149-159
  • 21 Xu D C, Zhong S Z, Kong J M et al.. Applied anatomy of the anterolateral femoral flap.  Plast Reconstr Surg. 1988;  82 305-310
  • 22 Kimata Y, Uchiyama K, Ebihara S, Nakatsuka T, Harii K. Anatomic variations and technical problems of the anterolateral thigh flap: a report of 74 cases.  Plast Reconstr Surg. 1998;  102 1517-1523
  • 23 Ao M, Uno K, Maeta M, Nakagawa F, Saito R, Nagase Y. De-epithelialised anterior (anterolateral and anteromedial) thigh flaps for dead space filling and contour correction in head and neck reconstruction.  Br J Plast Surg. 1999;  52 261-267
  • 24 Wei F C, Jain V, Celik N, Chen H C, Chuang D C, Lin C H. Have we found an ideal soft-tissue flap? An experience with 672 anterolateral thigh flaps.  Plast Reconstr Surg. 2002;  109 2219-2226 discussion 2227-2230
  • 25 Koshima I, Hosoda S, Inagawa K, Urushibara K, Moriguchi T. Free combined anterolateral thigh flap and vascularized fibula for wide, through-and-through oromandibular defects.  J Reconstr Microsurg. 1998;  14 529-534
  • 26 Koshima I. Free anterolateral thigh flap for reconstruction of head and neck defects following cancer ablation.  Plast Reconstr Surg. 2000;  105 2358-2360
  • 27 Kimata Y, Uchiyama K, Ebihara S et al.. Versatility of the free anterolateral thigh flap for reconstruction of head and neck defects.  Arch Otolaryngol Head Neck Surg. 1997;  123 1325-1331
  • 28 Demirkan F, Chen H C, Wei F C et al.. The versatile anterolateral thigh flap: a musculocutaneous flap in disguise in head and neck reconstruction.  Br J Plast Surg. 2000;  53 30-36
  • 29 Shieh S J, Chiu H Y, Yu J C, Pan S C, Tsai S T, Shen C L. Free anterolateral thigh flap for reconstruction of head and neck defects following cancer ablation.  Plast Reconstr Surg. 2000;  105 2349-2357 discussion 2358-2360
  • 30 Nakayama B, Hyodo I, Hasegawa Y et al.. Role of the anterolateral thigh flap in head and neck reconstruction: advantages of moderate skin and subcutaneous thickness.  J Reconstr Microsurg. 2002;  18 141-146
  • 31 Cipriani R, Contedini F, Caliceti U, Cavina C. Three-dimensional reconstruction of the oral cavity using the free anterolateral thigh flap.  Plast Reconstr Surg. 2002;  109 53-57
  • 32 Huang W C, Chen H C, Jain V et al.. Reconstruction of through-and-through cheek defects involving the oral commissure, using chimeric flaps from the thigh lateral femoral circumflex system.  Plast Reconstr Surg. 2002;  109 433-441 discussion 442-443
  • 33 Wolff K D, Grundmann A. The free vastus lateralis flap: an anatomic study with case reports.  Plast Reconstr Surg. 1992;  89 469-475 discussion 476-477
  • 34 Koshima I, Fukuda H, Soeda S. Free combined anterolateral thigh flap and vascularized iliac bone graft with double vascular pedicle.  J Reconstr Microsurg. 1989;  5 55-61
  • 35 Koshima I, Hosoda M, Moriguchi T, Hamanaka T, Kawata S, Hata T. A combined anterolateral thigh flap, anteromedial thigh flap, and vascularized iliac bone graft for a full-thickness defect of the mental region.  Ann Plast Surg. 1993;  31 175-180
  • 36 Kimata Y, Uchiyama K, Ebihara S et al.. Anterolateral thigh flap donor-site complications and morbidity.  Plast Reconstr Surg. 2000;  106 584-589
  • 37 Kuo Y R, Jeng S F, Kuo M H et al.. Free anterolateral thigh flap for extremity reconstruction: clinical experience and functional assessment of donor site.  Plast Reconstr Surg. 2001;  107 1766-1771
  • 38 Koshima I, Yamamoto H, Hosoda M, Moriguchi T, Orita Y, Nagayama H. Free combined composite flaps using the lateral circumflex femoral system for repair of massive defects of the head and neck regions: an introduction to the chimeric flap principle.  Plast Reconstr Surg. 1993;  92 411-420
  • 39 Schoeller T, Huemer G M, Shafighi M, Gurunluoglu R, Wechselberger G, Piza-Katzer H. Free anteromedial thigh flap: clinical application and review of literature.  Microsurgery. 2004;  24 43-48
  • 40 Koshima I, Soeda S, Yamasaki M, Kyou J. The free or pedicled anteromedial thigh flap.  Ann Plast Surg. 1988;  21 480-485
  • 41 Ao M, Nagase Y, Mae O, Namba Y. Reconstruction of posttraumatic defects of the foot by flow-through anterolateral or anteromedial thigh flaps with preservation of posterior tibial vessels.  Ann Plast Surg. 1997;  38 598-603
  • 42 Schoeller T, Shafighi M, Huemer G M, Wechselberger G, Piza-Katzer H. Coverage of pressure sores with free flaps.  Chirurgie. 2003;  74 671-676
  • 43 Koshima I, Hosoda M, Inagawa K, Moriguchi T, Orita Y. Free medial thigh perforator-based flaps: new definition of the pedicle vessels and versatile application.  Ann Plast Surg. 1996;  37 507-515
  • 44 Blondeel P N. One hundred free DIEP flap breast reconstructions: a personal experience.  Br J Plast Surg. 1999;  52 104-111
  • 45 Hamdi M, Weiler-Mithoff E M, Webster M H. Deep inferior epigastric perforator flap in breast reconstruction: experience with the first 50 flaps.  Plast Reconstr Surg. 1999;  103 86-95
  • 46 Koshima I, Soeda S. Inferior epigastric artery skin flaps without rectus abdominis muscle.  Br J Plast Surg. 1989;  42 645-648
  • 47 Futter C M, Webster M H, Hagen S, Mitchell S L. A retrospective comparison of abdominal muscle strength following breast reconstruction with a free TRAM or DIEP flap.  Br J Plast Surg. 2000;  53 578-583
  • 48 Beausang E S, McKay D, Brown D H et al.. Deep inferior epigastric artery perforator flaps in head and neck reconstruction.  Ann Plast Surg. 2003;  51 561-563
  • 49 Koshima I, Nanba Y, Tsutsui T, Takahashi Y, Watanabe A, Ishii R. Free perforator flap for the treatment of defects after resection of huge arteriovenous malformations in the head and neck regions.  Ann Plast Surg. 2003;  51 194-199
  • 50 Fujino T, Harasina T, Aoyagi F. Reconstruction for aplasia of the breast and pectoral region by microvascular transfer of a free flap from the buttock.  Plast Reconstr Surg. 1975;  56 178-181
  • 51 Verpaele A M, Blondeel P N, Van Landuyt K et al.. The superior gluteal artery perforator flap: an additional tool in the treatment of sacral pressure sores.  Br J Plast Surg. 1999;  52 385-391
  • 52 Allen R J, Tucker Jr C. Superior gluteal artery perforator free flap for breast reconstruction.  Plast Reconstr Surg. 1995;  95 1207-1212
  • 53 Blondeel P N. The sensate free superior gluteal artery perforator (S-GAP) flap: a valuable alternative in autologous breast reconstruction.  Br J Plast Surg. 1999;  52 185-193
  • 54 Spinelli H M, Fink J A, Muzaffar A R. The latissimus dorsi perforator-based fasciocutaneous flap.  Ann Plast Surg. 1996;  37 500-506
  • 55 Kim J T, Koo B S, Kim S K. The thin latissimus dorsi perforator-based free flap for resurfacing.  Plast Reconstr Surg. 2001;  107 374-382
  • 56 Guerra A B, Metzinger S E, Lund K M, Cooper M M, Allen R J, Dupin C L. The thoracodorsal artery perforator flap: clinical experience and anatomic study with emphasis on harvest techniques.  Plast Reconstr Surg. 2004;  114 32-41 discussion 42-43
  • 57 Marchetti C, Gessaroli M, Cipriani R, Contedini F, Frattarelli M, Staffa G. Use of “perforator flaps” in skull base reconstruction after tumor resection.  Plast Reconstr Surg. 2002;  110 1303-1309
  • 58 Schwabegger A, Ninković M, Brenner E, Anderl H. Seroma as a common donor site morbidity after harvesting the latissimus dorsi flap: observations on cause and prevention.  Ann Plast Surg. 1997;  38 594-597
  • 59 Titley O G, Spyrou G E, Fatah M F. Preventing seroma in the latissimus dorsi flap donor site.  Br J Plast Surg. 1997;  50 106-108
  • 60 Germann G, Bickert B, Steinau H U, Wagner H, Sauerbier M. Versatility and reliability of combined flaps of the subscapular system.  Plast Reconstr Surg. 1999;  103 1386-1399
  • 61 Van Landuyt K, Hamdi M, Blondeel P, Monstrey S. The compound thoracodorsal perforator flap in the treatment of combined soft-tissue defects of sole and dorsum of the foot.  Br J Plast Surg. 2005;  58 371-378
  • 62 Yoshimura M, Imura S, Shimamura K, Yamauchi S, Nomura S. Peroneal flap for reconstruction in the extremity: preliminary report.  Plast Reconstr Surg. 1984;  74 402-409
  • 63 Tsai F C, Yang J Y, Chuang S S, Chang S Y, Huang W C. Combined method of free lateral leg perforator flap with cervicoplasty for reconstruction of anterior cervical scar contractures: a new flap.  J Reconstr Microsurg. 2002;  18 185-190
  • 64 Wolff K D, Hölzle F, Nolte D. Perforator flaps from the lateral lower leg for intraoral reconstruction.  Plast Reconstr Surg. 2004;  113 107-113
  • 65 Pontén B. The fasciocutaneous flap: its use in soft tissue defects of the lower leg.  Br J Plast Surg. 1981;  34 215-220
  • 66 Carriquiry C, Aparecida Costa M, Vasconez L O. An anatomic study of the septocutaneous vessels of the leg.  Plast Reconstr Surg. 1985;  76 354-363
  • 67 Wolff K D, Stellmach R. The osteoseptocutaneous or purely septocutaneous peroneal flap with a supramalleolar skin paddle.  Int J Oral Maxillofac Surg. 1995;  24(1 Pt 1) 38-43
  • 68 Schusterman M A, Reece G P, Miller M J, Harris S. The osteocutaneous free fibula flap: is the skin paddle reliable?.  Plast Reconstr Surg. 1992;  90 787-793 discussion 794-798
  • 69 Martin D, Pascal J F, Baudet J et al.. The submental island flap: a new donor site. Anatomy and clinical applications as a free or pedicled flap.  Plast Reconstr Surg. 1993;  92 867-873
  • 70 Faltaous A A, Yetman R J. The submental artery flap: an anatomic study.  Plast Reconstr Surg. 1996;  97 56-60 discussion 61-62
  • 71 Sterne G D, Januszkiewicz J S, Hall P N, Bardsley A F. The submental island flap.  Br J Plast Surg. 1996;  49 85-89
  • 72 Kim J T, Kim S K, Koshima I, Moriguchi T. An anatomic study and clinical applications of the reversed submental perforator-based island flap.  Plast Reconstr Surg. 2002;  109 2204-2210
  • 73 Taylor G I, Townsend P, Corlett R. Superiority of the deep circumflex iliac vessels as the supply for free groin flaps. Clinical work.  Plast Reconstr Surg. 1979;  64 745-759
  • 74 Hartrampf Jr C R, Noel R T, Drazan L, Elliott F L, Bennett G K, Beegle P H. Ruben's fat pad for breast reconstruction: a peri-iliac soft-tissue free flap.  Plast Reconstr Surg. 1994;  93 402-407
  • 75 Safak T, Klebuc M J, Mavili E, Shenaq S M. A new design of the iliac crest microsurgical free flap without including the “obligatory” muscle cuff.  Plast Reconstr Surg. 1997;  100 1703-1709
  • 76 Kimata Y, Uchiyama K, Sakuraba M et al.. Deep circumflex iliac perforator flap with iliac crest for mandibular reconstruction.  Br J Plast Surg. 2001;  54 487-490
  • 77 Kimata Y. Deep circumflex iliac perforator flap.  Clin Plast Surg. 2003;  30 433-438
  • 78 Urken M L, Biller H F. A new bilobed design for the sensate radial forearm flap to preserve tongue mobility following significant glossectomy.  Arch Otolaryngol Head Neck Surg. 1994;  120 26-31
  • 79 Urken M L, Moscoso J F, Lawson W, Biller H F. A systematic approach to functional reconstruction of the oral cavity following partial and total glossectomy.  Arch Otolaryngol Head Neck Surg. 1994;  120 589-601
  • 80 Lyos A T, Evans G R, Perez D, Schusterman M A. Tongue reconstruction: outcomes with the rectus abdominis flap.  Plast Reconstr Surg. 1999;  103 442-447 discussion 448-449
  • 81 Beasley N J, Gilbert R W, Gullane P J, Brown D H, Irish J C, Neligan P C. Scalp and forehead reconstruction using free revascularized tissue transfer.  Arch Facial Plast Surg. 2004;  6 16-20
  • 82 Borah G L, Hidalgo D A, Wey P D. Reconstruction of extensive scalp defects with rectus free flaps.  Ann Plast Surg. 1995;  34 281-285 discussion 285-287
  • 83 Ylä-Kotola T M, Kauhanen M S, Koskinen S K, Asko-Seljavaara S L. Magnetic resonance imaging of microneurovascular free muscle flaps in facial reanimation.  Br J Plast Surg. 2005;  58 22-27
  • 84 Lutz B S. Aesthetic and functional advantages of the anterolateral thigh flap in reconstruction of tumor-related scalp defects.  Microsurgery. 2002;  22 258-264
  • 85 Yang J Y, Tsai F C, Chana J S, Chuang S S, Chang S Y, Huang W C. Use of free thin anterolateral thigh flaps combined with cervicoplasty for reconstruction of postburn anterior cervical contractures.  Plast Reconstr Surg. 2002;  110 39-46
  • 86 Urken M L, Weinberg H, Vickery C, Buchbinder D, Lawson W, Biller H F. Oromandibular reconstruction using microvascular composite free flaps. Report of 71 cases and a new classification scheme for bony, soft-tissue, and neurologic defects.  Arch Otolaryngol Head Neck Surg. 1991;  117 733-744
  • 87 Wei F C, Celik N, Chen H C, Cheng M H, Huang W C. Combined anterolateral thigh flap and vascularized fibula osteoseptocutaneous flap in reconstruction of extensive composite mandibular defects.  Plast Reconstr Surg. 2002;  109 45-52
  • 88 Wei F C, Demirkan F, Chen H C, Chen I H. Double free flaps in reconstruction of extensive composite mandibular defects in head and neck cancer.  Plast Reconstr Surg. 1999;  103 39-47
  • 89 Sanger J R, Matloub H S, Yousif N J. Sequential connection of flaps: a logical approach to customized mandibular reconstruction.  Am J Surg. 1990;  160 402-404
  • 90 Hallock G G. Simultaneous transposition of anterior thigh muscle and fascia flaps: an introduction to the chimera flap principle.  Ann Plast Surg. 1991;  27 126-131
  • 91 Cordeiro P G, Santamaria E. A classification system and algorithm for reconstruction of maxillectomy and midfacial defects.  Plast Reconstr Surg. 2000;  105 2331-2346 discussion 2347-2348
  • 92 Cordeiro P G, Disa J J. Challenges in midface reconstruction.  Semin Surg Oncol. 2000;  19 218-225
  • 93 Chana J S, Chen H C, Sharma R, Hao S P, Tsai F C. Use of the free vastus lateralis flap in skull base reconstruction.  Plast Reconstr Surg. 2003;  111 568-574 discussion 575
  • 94 Urken M L, Catalano P J, Sen C, Post K, Futran N, Biller H F. Free tissue transfer for skull base reconstruction analysis of complications and a classification scheme for defining skull base defects.  Arch Otolaryngol Head Neck Surg. 1993;  119 1318-1325
  • 95 Clayman G L, DeMonte F, Jaffe D M et al.. Outcome and complications of extended cranial-base resection requiring microvascular free-tissue transfer.  Arch Otolaryngol Head Neck Surg. 1995;  121 1253-1257
  • 96 Schliephake H, Schmelzeisen R, Samii M, Sollmann W P. Microvascular reconstruction of the skull base: indications and procedures.  J Oral Maxillofac Surg. 1999;  57 233-239
  • 97 Neligan P C, Mulholland S, Irish J et al.. Flap selection in cranial base reconstruction.  Plast Reconstr Surg. 1996;  98 1159-1166 discussion 1167-1168
  • 98 Fisher J, Jackson I T. Microvascular surgery as an adjunct to craniomaxillofacial reconstruction.  Br J Plast Surg. 1989;  42 146-154
  • 99 Mulholland S, Boyd J B, McCabe S et al.. Recipient vessels in head and neck microsurgery: radiation effect and vessel access.  Plast Reconstr Surg. 1993;  92 628-632
  • 100 Arinci A, Topalan M, Aydin I et al.. Effects of early pre- and postoperative irradiation on the healing of microvascular anastomoses.  J Reconstr Microsurg. 2000;  16 573-576
  • 101 Celik N, Wei F C, Lin C H et al.. Technique and strategy in anterolateral thigh perforator flap surgery, based on an analysis of 15 complete and partial failures in 439 cases.  Plast Reconstr Surg. 2002;  109 2211-2216 discussion 2217-2218
  • 102 Hallock G G. Discussion. Have we found an ideal soft-tissue flap? An experience with 672 anterolateral thigh flaps.  Plast Reconstr Surg. 2002;  109 2227-2230
  • 103 Yang K C, Leung J K, Chen J S. Double-paddle peroneal tissue transfer for oromandibular reconstruction.  Plast Reconstr Surg. 2000;  106 47-55

Jagdeep S ChanaM.D. F.R.C.S. 

Department of Plastic and Reconstructive Surgery

Mount Vernon Hospital, Northwood, Middlesex HA6 2RN, UK

Email: jchana@doctors.org.uk

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