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Synlett 1990; 1990(8): 479-480
DOI: 10.1055/s-1990-21134
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The Direct Conversion of 1,2-Cyclic Sulphates into Alkenes

Christopher M. D. Beels* , Mark J. Coleman, Richard  J. K. Taylor
  • *Process Research Department, Glaxo Group Research Ltd., Ware, Herts., SG12 0DP, England
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Publication Date:
08 March 2002 (online)

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1,2-Cyclic sulphates prepared from 1,2-diols can be converted into alkenes by treatment with sodium naphthalenide in tetrahydrofuran. Preliminary details of the scope and limitations of this new procedure are described.