Download PDF
Synlett 1996; 1996(2): 187-188
DOI: 10.1055/s-1996-5350
letter
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

A ‘3+1’ Approach to Monofunctionalized Alkyl Porphyrins

J. L. Sessler* , J. W. Genge, A. Urbach, P. Sansom
  • *Department of Chemistry and Biochemistry, University of Texas at Austin, Austin, Texas 78712, U.S.A.
Further Information

Publication History

Publication Date:
31 December 2000 (online)

  PDF Download  Permissions and Reprints All articles of this category

A new synthesis of a monofunctionalized β-substituted alkyl porphyrin, 2-(methoxycarbonylethyl)-8,12,13,17-tetraethyl-3,7,18-trimethyl porphyrin (1), is described. It involves the use of a novel ‘3+1’ connectivity approach. Specifically, the mono-substituted tripyrrane, 2,5-bis(5-carboxy-4-ethyl-3-methylpyrrol-2-ylmethyl)-3-(methoxycarbonylethyl)-4-methylpyrrole, was condensed with a doubly activated monomeric pyrrole, 3,4-diethyl-2,5-diformylpyrrole. This yielded porphyrin 1 in 35% yield.

porphyrin - tripyrrane - ‘3+1’ - monohook - diformylpyrrole