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Synlett 1997; 1997(12): 1400-1402
DOI: 10.1055/s-1997-1041
DOI: 10.1055/s-1997-1041
letter
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A Convenient Synthesis of Nitrogen-Containing Heterocycles Bearing Amino Substituents from Heteroaryl Triflates
Further Information
Publication History
Publication Date:
31 December 2000 (online)
Nitrogen-containing heterocycles bearing amino substituents were prepared by the reaction of the corresponding nitrogen-containing heteroaryl triflates with amines. The reaction affords good results with primary and secondary amines, and with aliphatic and aromatic amines. The whole triflation/amination process can also be conducted as a one-pot operation.
heteroaryl triflates - substitution - heterocycles - quinolines - pyridines