Synthesis of 3-Nitro-1H-indole-2-carboxylic Acid Ethyl Ester Derivatives from Baylis-Hillman Adducts

Abstract

A simple and direct synthesis of 3-nitro-1H-indole-2-carboxylic acid ethyl ester derivatives from acetylated Baylis-Hillman adducts of 2-nitrobenzaldehydes is described.

Key words

indoles - heterocycle - rearrangement - ring-closure - Baylis-Hillman

References

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