Synlett 2016; 27(15): 2178-2182
DOI: 10.1055/s-0035-1562489
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© Georg Thieme Verlag Stuttgart · New York

Enantioselective Organocatalytic Intramolecular Morita–Baylis–Hillman Reaction of Some Unusual Substrates

Bishnupada Satpathi
Organic Synthesis and Catalysis Lab, Department of Chemical Sciences, Indian Institute of Science Education and Research (IISER) Mohali, Knowledge City, Sector 81, S. A. S. Nagar, Manuali PO, Punjab 140306, India   Email: ramsastry@iisermohali.ac.in
,
S. S. V. Ramasastry*
Organic Synthesis and Catalysis Lab, Department of Chemical Sciences, Indian Institute of Science Education and Research (IISER) Mohali, Knowledge City, Sector 81, S. A. S. Nagar, Manuali PO, Punjab 140306, India   Email: ramsastry@iisermohali.ac.in
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Further Information

Publication History

Received: 04 May 2016

Accepted after revision: 20 May 2016

Publication Date:
22 June 2016 (online)


Abstract

The hypothesis and rationale behind our recent contribution towards the development of an enantioselective organocatalytic intramolecular Morita–Baylis–Hillman (IMBH) reaction, leading to the synthesis of an array of cyclopentannulated arenes and heteroarenes, is discussed. The latest advancement has addressed some of the shortcomings of the MBH reaction. In addition, it is believed that this study paves the way for the consideration of new possibilities in MBH chemistry.