ortho-Heterobimetallic Arylene Complex: A New Platform for Regioselective Difunctionalization

Abstract

Regioselective ortho difunctionalization of arenes is highly desirable yet challenging in organic synthesis. Here, we briefly discuss various methods for ortho difunctionalization of arenes and highlight a novel ortho-heterobimetallic arylene complex enabled by heterobimetallic synergism, which shows great potential in regioselective ortho difunctionalizations.

1 Introduction

2 Distinct Reactivity of C–Fe and C–Ti Bonds

3 E/E′ ODFs by Fe/Ti-Heterobimetallic Intermediate

4 Nu/E ODFs by Fe/Ti -Heterobimetallic Intermediate

5 Summary and Outlook

Key words

bimetallic - synergism - regioselectivity - difunctionalization - iron - titanium

Publikationsverlauf

Eingereicht: 09. April 2023

Angenommen nach Revision: 03. Mai 2023

Accepted Manuscript online:
03. Mai 2023

Artikel online veröffentlicht:
26. Mai 2023

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