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Synfacts 2008(12): 1251-1251  
DOI: 10.1055/s-0028-1087292
Synthesis of Natural Products and Potential Drugs
© Georg Thieme Verlag Stuttgart ˙ New York

Synthesis of (±)-Lyconadin A

Contributor(s): Philip Kocienski, Stewart Eccles
A. Bisai, S. P. West, R. Sarpong*
University of California, Berkeley, USA
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Publication History

Publication Date:
20 November 2008 (online)

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Significance

()-Lyconadin A is an unusual member of the Lycopodium alkaloid family, members of which possess varied biological activities. Reported here is a method to produce miscellaneous Lycopodium alkaloids from a common intermediate, forming the tetracyclic core by an oxidative C-N bond forming reaction.