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Synfacts 2009(2): 0154-0154  
DOI: 10.1055/s-0028-1087495
Synthesis of Materials and Unnatural Products
© Georg Thieme Verlag Stuttgart ˙ New York

Tyrosinase Activity Sensor

Contributor(s): Timothy M. Swager, Jeewoo Lim
X. Feng, F. Feng, M. Yu, F. He, Q. Xu, H. Tang, S. Wang*, Y. Li, D. Zhu
Institute of Chemistry, Chinese Academy of Sciences, Beijing, P. R. of China
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Publikationsdatum:
22. Januar 2009 (online)

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Significance

The authors report a synthesis of a fluorescent probe for sensing tyrosinase activity. This water-soluble probe could potentially be used to sense melanoma cancer cells, for which accumulated tyrosinase is a marker.