Syntheses of Cassiarins A and B

Y.-S. Yao; Z.-J. Yao

doi:10.1055/s-0028-1087601

RSS-Feed abonnieren

Bitte kopieren Sie die angezeigte URL und fügen sie dann in Ihren RSS-Reader ein.

https://www.thieme-connect.de/rss/thieme/de/10.1055-s-00000131.xml

Teilen / Bookmarken

Facebook X Linkedin Weibo

PDF herunterladen

Synfacts 2009(2): 0120-0120
DOI: 10.1055/s-0028-1087601

Synthesis of Natural Products and Potential Drugs

Syntheses of Cassiarins A and B

Contributor(s): Philip Kocienski, Indu Dager
Y.-S. Yao, Z.-J. Yao*
Shanghai Institute of Organic Chemistry and University of Science and Technology of China, Hefei, P. R. of China

Weitere Informationen

Publikationsverlauf

Publikationsdatum:
22. Januar 2009 (online)

Lizenzen und Reprints

Significance

Cassiarins A and B are isolated form Cassia siamea which has been used as traditional medicine for the treatment of malaria. Both cassiarins A and B show potent antiplasmodial activity against Plasmodium falciparum with an IC₅₀ of 0.005 and 6.9 mg/mL, respectively.