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Synfacts 2009(2): 0202-0202  
DOI: 10.1055/s-0028-1087651
Metal-Mediated Synthesis
© Georg Thieme Verlag Stuttgart ˙ New York

Rare Earth Metal Catalyzed Cross-Coupling of Isocyanides

Contributor(s): Paul Knochel, Andreas J. Wagner
W.-X. Zhang, M. Nishiura, Z. Hou*
RIKEN Advanced Science Institute, Saitama, Japan and Peking University, Beijing, P. R. of China
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Publication History

Publication Date:
22 January 2009 (online)

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Significance

Rare-earth metal half-sandwich complexes bearing a silylene-linked Cp-amido-ligand have been found to serve as efficient catalysts for the catalytic cross-coupling between ­terminal alkynes and alkyl isocyanides to form 1-aza-1,3-enynes in unprecedented Z-selectivity.