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Synfacts 2009(2): 0192-0192
DOI: 10.1055/s-0028-1087652
DOI: 10.1055/s-0028-1087652
Metal-Mediated Synthesis
© Georg Thieme Verlag
Stuttgart ˙ New York
Efficient Cu/Phenanthroline-Catalyzed Arylation of sp² C-H Bonds
H.-Q. Do, R. M. Kashif Khan, O. Daugulis*
University of Houston, USA
Further Information
Publication History
Publication Date:
22 January 2009 (online)
Significance
The authors report a general method for the copper-catalyzed arylation of sp² C-H bonds with pKa values lower than 35. The reaction proceeds through the use of lithium alkoxides or potassium phosphate as bases.