Synthesis of Phoslactomycin A

C. M. König; B. Gebhardt; C. Schleth; M. Dauber; U. Koert

doi:10.1055/s-0029-1218329

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Synfacts 2009(12): 1317-1317
DOI: 10.1055/s-0029-1218329

Synthesis of Natural Products and Potential Drugs

Synthesis of Phoslactomycin A

Contributor(s): Philip Kocienski
C. M. König, B. Gebhardt, C. Schleth, M. Dauber, U. Koert*
Philipps Universität Marburg, Germany

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Publication History

Publication Date:
20 November 2009 (online)

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Significance

The first total synthesis of phoslactomycin A is reported featuring Liebeskind’s copper(I) thiophene-2-carboxylate mediated coupling between alkenyl stannane F and iodoalkene E as a key fragment linkage reaction.