Download PDF
Synfacts 2010(1): 0076-0076  
DOI: 10.1055/s-0029-1218508
Metal-Catalyzed Asymmetric Synthesis and Stereoselective Reactions
© Georg Thieme Verlag Stuttgart ˙ New York

Catalytic Oxidative Desymmetrization of meso-Secondary Diols

Contributor(s): Hisashi Yamamoto, Zhi Li
T. Suzuki*, K. Ghozati, T. Katoh, H. Sasai
Osaka University and Tohoku Pharmaceutical University, Sendai, Japan
Further Information

Publication History

Publication Date:
21 December 2009 (online)

    Permissions and Reprints

Significance

The oxidative desymmetrization of meso-diols is an efficient way to synthesize hydroxyl carbonyl compounds. In this work, the iridium complex catalyzed oxidative desymmetrization of several cyclic and acyclic meso-diols was accomplished with high yields and high enantio­selectivities.