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Synfacts 2010(6): 0626-0626
DOI: 10.1055/s-0029-1219853
DOI: 10.1055/s-0029-1219853
Synthesis of Natural Products and Potential Drugs
© Georg Thieme Verlag
Stuttgart ˙ New York
Synthesis of Phostriecin and Sultriecin
C. P. Burke, N. Haq, D. L. Boger*
The Scripps Research Institute, La Jolla, USA
Weitere Informationen
Publikationsverlauf
Publikationsdatum:
20. Mai 2010 (online)
![](https://www.thieme-connect.de/media/synfacts/201006/lookinside/thumbnails/10.1055-s-0029-1219853-1.jpg)
Significance
Phostriecin (originally called sultriecin) was isolated in 1992. The original structure was thought to be the analogous C9 sulfate ester (now called sultriecin). Synthesis of this proposed structure led to a distinct difference in the ¹H NMR spectrum. Therefore, the revised structure phostriecin was prepared and shown to match the data of the originally isolated natural product.