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Synfacts 2010(8): 0930-0930  
DOI: 10.1055/s-0030-1257756
Metal-Mediated Synthesis
© Georg Thieme Verlag Stuttgart ˙ New York

Copper-Catalyzed Direct Amination of Azoles with Chloroamines at Room Temperature

Contributor(s): Paul Knochel, Andreas J. Wagner
T. Kawano, K. Hirano, T. Satoh, M. Miura*
Osaka University, Suita, Japan
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Publikationsdatum:
22. Juli 2010 (online)

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Significance

Herein, N-chloroamines are introduced as readily available and effective nitrogen sources for heteroaromatic C-H functionalization by a copper-catalyzed direct amination of azoles.