RSS-Feed abonnieren
Bitte kopieren Sie die angezeigte URL und fügen sie dann in Ihren RSS-Reader ein.
https://www.thieme-connect.de/rss/thieme/de/10.1055-s-00000131.xml
Synfacts 2010(9): 1089-1089
DOI: 10.1055/s-0030-1257984
DOI: 10.1055/s-0030-1257984
Polymer-Supported Synthesis
© Georg Thieme Verlag
Stuttgart ˙ New York
Aza-Michael Addition in Alkaline Al2O3
X. Ai, X. Wang*, J.-M. Liu, Z.-M. Ge, T.-M. Cheng, R.-T. Li*
Peking University, Beijing, P. R. of China
Weitere Informationen
Publikationsverlauf
Publikationsdatum:
23. August 2010 (online)
![](https://www.thieme-connect.de/media/synfacts/201009/lookinside/thumbnails/10.1055-s-0030-1257984-1.jpg)
Significance
The alkaline Al2O3 mediated aza-Michael addition of aromatic or aliphatic amines (primary or secondary) to electron-deficient alkenes was described. The aza-Michael addition of aniline to acrylonitrile was carried out with alkaline Al2O3 to afford 3-(phenylamino)propionitrile 3a in 98% yield.