Substitution of Silanes with Grignard Reagents

Significance

A practical substitution reaction of silanes with Grignard reagents in the presence of lithium chloride is described. The reaction rate of allyl and aryl Grignard reagents is greatly accelerated. For many examples, LiCl can be used only in catalytic amounts (5 mol%). Even inherently less reactive alkylsilanes and sterically demanding Grignard reagents give excellent yields.