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Synfacts 2011(4): 0361-0361  
DOI: 10.1055/s-0030-1259640
Synthesis of Natural Products and Potential Drugs
© Georg Thieme Verlag Stuttgart ˙ New York

Synthesis of Sintokamides A, B and E

Contributor(s): Steven V. Ley, Sean Newton
Z. Gu, A. Zakarian*
University of California at Santa Barbara, USA
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Publikationsverlauf

Publikationsdatum:
18. März 2011 (online)

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Significance

Sintokamides A-E were isolated from the marine sponge Dysidea sp. and represent a rare class of halogenated natural products. Sintokamides B and E were synthesized using the trichloromethyl derivative of J and l-leucine methyl ester hydrochloride instead of J, respectively (not shown).