Subscribe to RSS
Please copy the URL and add it into your RSS Feed Reader.
https://www.thieme-connect.de/rss/thieme/en/10.1055-s-00000131.xml
Synfacts 2011(11): 1233-1233
DOI: 10.1055/s-0031-1289200
DOI: 10.1055/s-0031-1289200
Metal-Mediated Synthesis
© Georg Thieme Verlag
Stuttgart ˙ New York
Oxidation of Silyl Enol Ethers with Metal Nitrites
M. Baidya, H. Yamamoto*
The University of Chicago, USA
Further Information
Publication History
Publication Date:
19 October 2011 (online)
Significance
The authors disclose an efficient and straightforward protocol for the preparation of a new nitroso reagent. These are used in oxidation reactions of silyl enol ethers affording keto oximes in high yield. The oxidizing agent is triisopropyl silyl nitrite which is generated in situ from silver nitrite and triisopropylsilyl chloride.