Expanding Structural Diversity; Removable and Manipulable Directing Groups for C–H Activation

Abstract

The need to use a static directing group represents a ­major limitation for the emerging field of ortho-selective C–H ­activation and functionalization. Chemistry was recently developed that allowed partial removal or minor transformations for certain directing groups. Our recent work demonstrated that triazenes were a class of excellent directing groups for C–H activation/functionalization, and subsequent chemical manipulations generated key compounds with synthetic versatility.

Key words

C–H activation - directing groups - transition metals - ­catalysis - protecting groups

• References and Notes


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