4-Chloropyrazolopyridine as a Tunable, Covalently Acting SNAr Electrophile

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Synfacts 2024; 20(08): 0872
DOI: 10.1055/s-0043-1774946

Innovative Drug Discovery and Development

4-Chloropyrazolopyridine as a Tunable, Covalently Acting S_NAr Electrophile

Contributor(s):

Antonia F. Stepan (Roche)

,

Nicholas A. Meanwell (Baruch S. Blumberg Institute, U. Michigan, Rutgers U.)

covalent inhibition - warhead design - S_NAr reaction

Article published online:
25 July 2024

Georg Thieme Verlag KG
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