Synlett 1997; 1997(8): 939-940
DOI: 10.1055/s-1997-952
letter
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

Synthesis of an N-Alkyl Derivative of 2'-Deoxyisoguanosine

Janos T. Kodra1 , Steven A. Benner2
  • 1Department of Chemistry, Swiss Federal Institute of Technology, Universitätsstrasse 16, CH 8092 Zürich, Switzerland
  • 2Department of Chemistry, University of Florida, Gainesville, Florida 32611, USA, Tel (352) 392 7773; Fax (352) 846 2580
Further Information

Publication History

Publication Date:
31 December 2000 (online)

3',5'-O-bis-tert-butyldimethylsilyl-2'-deoxyguanosine is converted in two steps to 3',5'-O-tert-butyldimethylsilyl-6-O-aryl-2'-deoxyxanthosine. This compound is used to make a 2'-deoxyisoguanosine analog with a functionalized side chain.