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Synfacts 2006(1): 0004-0004
DOI: 10.1055/s-2005-921660
DOI: 10.1055/s-2005-921660
Synthesis of Natural Products and Potential Drugs
© Georg Thieme Verlag Stuttgart · New York
Synthesis of Glycocinnaspermicin D
T. Nishiyama, M. Isobe, Y. Ichikawa*
Kochi University and Nagoya University, Japan
Weitere Informationen
Publikationsverlauf
Publikationsdatum:
16. Dezember 2005 (online)
Significance
Glycocinnaspermicin D has a broad spectrum of activity against Gram-negative bacteria. A major challenge in the synthesis was the construction of the urea bridge between two highly functionalized amino sugars.