Subscribe to RSS
Please copy the URL and add it into your RSS Feed Reader.
https://www.thieme-connect.de/rss/thieme/en/10.1055-s-00000131.xml
Synfacts 2006(1): 0011-0011
DOI: 10.1055/s-2005-921668
DOI: 10.1055/s-2005-921668
Synthesis of Natural Products and Potential Drugs
© Georg Thieme Verlag Stuttgart · New York
Synthesis of Viridiofungin A
A. Pollex, A. Millet, J. Müller, H. Hiersemann*, L. Abraham
Technische Universät Dresden, Germany
Further Information
Publication History
Publication Date:
16 December 2005 (online)
Significance
Viridiofungins are secondary metabolites isolated from the fungi Trichoderma viride and belong to the alkyl citrate family of compounds. They demonstrate potent fungicidal activity which is due to multiple modes of action. These natural products may also have anti-cancer activity. The synthesis of the triesters of the natural and nonnatural diastereomers of viridiofungin A, A2 and A4 is reported.