RSS-Feed abonnieren
Bitte kopieren Sie die angezeigte URL und fügen sie dann in Ihren RSS-Reader ein.
https://www.thieme-connect.de/rss/thieme/de/10.1055-s-00000131.xml
Synfacts 2006(2): 0127-0127
DOI: 10.1055/s-2005-924782
DOI: 10.1055/s-2005-924782
Metal-Catalyzed Asymmetric Synthesis and Stereoselective Reactions
© Georg Thieme Verlag Stuttgart · New York
Regioselective Hydrosilylation of Unsymmetrical Aryl Alkynes
A. Hamze, O. Provot, M. Alami*, J.-D. Brion
Universite Paris-Sud XI, France
Weitere Informationen
Publikationsverlauf
Publikationsdatum:
23. Januar 2006 (online)
![](https://www.thieme-connect.de/media/synfacts/200602/lookinside/thumbnails/10.1055-s-2005-924782-1.jpg)
Significance
The PtO2-catalyzed hydrosilylation of unsymmetrical aryl alkynes gave preferentially the α-silylated product when an ortho-substituent on the aryl group was present, regardless of whether the ortho-substituent was an electron-donating or electron-withdrawing one. para-Substituents showed a weaker α-silylation directing effect. PtO2 displayed a more powerful directing effect than H2PtCl6 and also resulted in higher yields since it does not promote alkyne reduction.