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Synfacts 2006(11): 1085-1085  
DOI: 10.1055/s-2006-949385
Synthesis of Natural Products and Potential Drugs
© Georg Thieme Verlag Stuttgart · New York

Synthesis of (-)-Sordarin

Contributor(s): Philip Kocienski, John Cooksey
S. Chiba, M. Kitamura, K. Narasaka*
The University of Tokyo, Japan
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Publikationsdatum:
24. Oktober 2006 (online)

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Significance

(-)-Sordarin, a metabolite isolated from the fungus Sordaria araneosa, exhibits potent anti-fungal activity. Narasaka and co-workers report the first stereoselective synthesis of (-)-sordarin.