Download PDF
Synfacts 2007(11): 1172-1172  
DOI: 10.1055/s-2007-991257
Metal-Catalyzed Asymmetric Synthesis and Stereoselective Reactions
© Georg Thieme Verlag Stuttgart · New York

Enantioselective Synthesis of 1,2-Nitro Alcohols

Contributor(s): Mark Lautens, Frédéric Ménard
T. Arai*, M. Watanabe, A. Yanagisawa
Chiba University, Japan
Further Information

Publication History

Publication Date:
23 October 2007 (online)

    Permissions and Reprints

Significance

The present catalytic system is the simplest reported so far for the Henry reaction. The key is the design of a non-C 2 symmetrical ligand L1. The conditions are convenient and the catalyst tolerated air and moisture (copper hydrate salts can be used).